Nphp Complex

Mouse Tctn1 genetically interacts with NPHP complex genes but not MKS

Subcellular localization of the NPHP molecules nephrocystins

NPHP proteins are binding partners of nucleoporins at the base of the

A Longitudinal section of a diseased NPHP kidney compared with a

Figure 1 from MKS and NPHP modules cooperate to establish basal body

NPHP proteins function at the ciliary gate transition zone A

MKSMKSR and NPHP proteins form part of a functional interaction

ANKS6 forms a complex with NEK8 INVS NPHP3 and HIF1AN a

A Longitudinal section of a diseased NPHP kidney compared with a

Wnt component expression in normal PKD and NPHP kidneys The listed

MKSMKSR and NPHP proteins are organized hierarchically as modules and

C elegans NPHP genes synthetically interact with bbs5 to affect

Susceptibility of nphp mutants in response to depletion of additional

Wnt component expression in normal PKD and NPHP kidneys The listed

NPHP proteins are binding partners of nucleoporins at the base of the

A Longitudinal section of a diseased NPHP kidney compared with a

Interaction of NPHP1 Δ(49-110) with other NPHP proteins. Expression ...

Interaction of NPHP1 49110 with other NPHP proteins Expression

No obvious polarity defects in NPHP knockdown cells Immunostaining of

NPHP genes available for testing via UK and European gene testing

NPHP gene expression during cell polarization and generation of NPHP

PDF A complex of BBS1 and NPHP7 is required for cilia motility in

HYLS1 depletion interrupts the assembly of NPHP module at transition

PDF Tectonic Proteins Are Important Players in NonMotile Ciliopathies

Genetic interactions between transition zone complexes and the BBSome

Mapping the NPHPJBTSMKS Protein Network Reveals Ciliopathy Disease

Photoreceptor Sensory Cilium Traversing the Ciliary Gate

Tectonic Proteins Are Important Players in NonMotile Ciliopathies

Superresolution microscopy reveals that disruption of ciliary

Subcellular localization of protein encoded by monogenic genes of

A Model of NPHP1SH3 PDB code 1S1N surface representation in

NephronophthisisPathobiology and Molecular Pathogenesis of a Rare

The EF hand is necessary for proper NPHP2 localization and

Figure 1 from Functional characterization of the C elegans

Identification of NPHP4 c1490C G homozygous pathogenic variant that

NPHP4 is localized to the transition zone Isolated nucleoflagellar

SPATA7 interacts with members of the NPHPRPGR complex a

Model of ARL3UNC119bRP2dependent ciliary targeting of NPHP3cystin

Renal histology of patient A131 II4 Morphologic changes are

Mapping the NPHPJBTSMKS Protein Network Reveals Ciliopathy Disease

nphp2 is the ortholog of mammalian INVS is expressed in ciliated

Nephronophthisis Disease Mechanisms of a Ciliopathy PMC

SIM of two ciliary localization patterns of NPHP3 A SIM IF of NPHP3

Localization of fulllength and truncated NPHP4 in multiciliated cells

Drug screen in NPHP1 urinederived renal epithelial cells URECs A

Nephronophthisis NPHP Kidney Care UK

NPHP4F83L and NPHP4F903S localization relative to MKSR2

NephronophthisisPathobiology and Molecular Pathogenesis of a Rare

Superresolution microscopy reveals that disruption of ciliary

Nephronophthisis PMC

Moran CORE NPHP1Associated Retinal Degeneration

Schematic of nuclear and ciliary gating complexes A At the nuclear

MKS6 and NPHP4 are collectively required for BBTZ attachments to

Hippo signaling through the primary cilium A In the unstimulated

PDF Comparative Genomic Analyses of the Human NPHP1 Locus Reveal

Repurposing small molecules for nephronophthisis and related renal

MKSNPHP proteins are required for ciliary gate function but not for

NPHP2GFP ARL13GFP and GFPUNC119 colabel with GT335 staining

The Nterminal region of centrosomal protein 290 CEP290 restores

Functional interactions between five TZassociated proteins MKS1

Clinical and genetic characteristics of Japanese nephronophthisis

nphp2 single arl13 nphp2 double and arl13 hdac6 nphp2 triple

nphp1 and nphp4 mutants have misshaped long and stunted cilia A

Superresolution microscopy reveals that disruption of ciliary

PKD2GFP localizes to abnormally formed CEM cilia in nphp1 and nphp4

Mapping the NPHPJBTSMKS Protein Network Reveals Ciliopathy Disease

The JoubertMeckelNephronophthisis Spectrum of Ciliopathies

Mapping the NPHPJBTSMKS Protein Network Reveals Ciliopathy Disease

Genetics defects underlying NPHP associated features and other

ADAMTS9 variants identified in patients with NPHP A Pedigree of the

PDF Comparative Genomic Analyses of the Human NPHP1 Locus Reveal

SPATA7 interacts with members of the NPHPRPGR complex a

nphp2 mutants are moderately dye filling defective and have defects in

Moran CORE NPHP1Associated Retinal Degeneration

nphp2 mutants are moderately dye filling defective and have defects in

Nephronophthisis and related syndromes PMC

nphp2 is the ortholog of mammalian INVS is expressed in ciliated

NPC(核孔复合物(nuclear pore complex,NPC))_360百科

NPCnuclear pore complexNPC360

Nphp4 synDyf enhancer mutagenesis screen A Illustration depicting

Immunohistochemistry and immunofluorescence staining for Niban1 in

Mapping the NPHPJBTSMKS Protein Network Reveals Ciliopathy Disease

NephronophthisisAssociated CEP164 Regulates Cell Cycle Progression

Classification of kidney cells of NPHP1 and wildtype mice by

Frontiers Many GenesOne Disease Genetics of Nephronophthisis NPHP

Cystic diseases of kidney PPTX

Directed yeast twohybrid assay reveals NUPNPHP interactions The

Distribution of molecular nephronophthisis NPHP diagnoses in 18

Ciliopathies

Nephrocystindeficient respiratory epithelial cells form normal cilia

Shared and distinct mechanisms of compartmentalized and cytosolic

Nephronophthisis and related syndromes PMC

Mapping the NPHPJBTSMKS Protein Network Reveals Ciliopathy Disease

NephronophthisisMedullary Cystic Kidney Disease Abdominal Key

FileAComplexofBBS1andNPHP7IsRequiredforCiliaMotilityin

ADAMTS9 variants identified in patients with NPHP A Pedigree of the

MKSNPHP module proteins control ciliary shedding at the transition

Frontiers Many GenesOne Disease Genetics of Nephronophthisis NPHP

CEM CEP and OLQ ciliary ultrastructure is abnormal in nphp4 mutants

NephronophthisisPathobiology and Molecular Pathogenesis of a Rare

Extrarenal manifestations of nephronophthisis and their associated

Characterization of nphp1deficient zebrafish A Exon 15 of zebrafish

Resilience of nphp4 mutant zebrafish lines against MOmediated nphp4

Mapping the NPHPJBTSMKS Protein Network Reveals Ciliopathy Disease

SynDyf genetic interactions between nphp2 and TZassociated genes

Mapping the NPHPJBTSMKS Protein Network Reveals Ciliopathy Disease

Diseased condition of the kidneys Discussion Nephronophthisis is

PDF Assessing the pathogenic potential of human Nephronophthisis

Are renal ciliopathies replication stressed out Trends in Cell Biology

The nphp2 and arl13 Genetic Modules Interact to Regulate Ciliogenesis

Superresolution microscopy reveals that disruption of ciliary

NephronophthisisMedullary Cystic Kidney Disease Abdominal Key

A schematic diagram summarizing relative locations of inversin NPHP2

The nphp2 and arl13 Genetic Modules Interact to Regulate Ciliogenesis

Flowchart for a suggested genotyping strategy in nephronophthisis

PPT - Felnőttkorban felismert hereditaer nephropathiák PowerPoint ...

PPT Felnttkorban felismert hereditaer nephropathik PowerPoint

CEM CEP and OLQ ciliary ultrastructure is abnormal in nphp4 mutants

The synthetic dyefilling defective phenotype of arl13 nphp2 mutants

Transistion Zone Nphp

Nephronophthisis Medullary Cystic Disease Complex

Nephronophthisis Medullary Cysts Disease Complex

NDHP Colenel

Nphp5 Cilium

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