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Tp53 R273h

TP53 G245C and R273H mutants promoted tumor cells invasion and ...

TP53 G245C and R273H mutants promoted tumor cells invasion and

TP53 G245C and R273H mutants accelerated the proliferation activities ...

TP53 G245C and R273H mutants accelerated the proliferation activities

Mutant TP53 G245C and R273H promote cellular malignancy in esophageal ...

Mutant TP53 G245C and R273H promote cellular malignancy in esophageal

(PDF) Mutant TP53 G245C and R273H promote cellular malignancy in ...

PDF Mutant TP53 G245C and R273H promote cellular malignancy in

Gain of Function p53 mutant R273H confers distinct methylation profiles ...

Gain of Function p53 mutant R273H confers distinct methylation profiles

Overview of p.R273 mutations in TP53 used to design crRNAs for ...

Overview of pR273 mutations in TP53 used to design crRNAs for

A Xray crystal structure of solvated human R273H mutant p53 core

Localization of TP53 mutations in GC samples from Eastern Europe ...

Localization of TP53 mutations in GC samples from Eastern Europe

Efficient Correction of Oncogenic KRAS and TP53 Mutations through ...

Efficient Correction of Oncogenic KRAS and TP53 Mutations through

Gain-of-Function Mutant p53 R273H Interacts with Replicating DNA and ...

GainofFunction Mutant p53 R273H Interacts with Replicating DNA and

Intermolecular interactions formed in the R273H mutant p53 active site

p53 R273H mutant enhanced tumor sphere formation and CSCs among colon

Comparison of the mutation frequencies of TP53 in TTs and ANTTs. The ...

Comparison of the mutation frequencies of TP53 in TTs and ANTTs The

Tumors that harbor a mut-p53 allele often retain wild-type TP53 A The ...

Tumors that harbor a mutp53 allele often retain wildtype TP53 A The

Effect of p53 R273H mutant on wound healing of colon cancer cells. A ...

Effect of p53 R273H mutant on wound healing of colon cancer cells A

TP53 missense–specific transcriptional plasticity drives resistance ...

TP53 missensespecific transcriptional plasticity drives resistance

ID1 suppression in PC3 cells expressing p53 R273H and ID1TP53 double

TP53 and its downstream proteins' expression levels. a The expression ...

TP53 and its downstream proteins expression levels a The expression

Common cancer mutations R175H and R273H drive the p53 DNA-binding ...

Common cancer mutations R175H and R273H drive the p53 DNAbinding

Quantitative detections of TP53 gene mutations improve the diagnosis ...

Quantitative detections of TP53 gene mutations improve the diagnosis

| Tp53 mutation may promote WISP1 expression in SH-PAN and PDAC cells ...

Tp53 mutation may promote WISP1 expression in SHPAN and PDAC cells

a TP53 mutations and inactivations may enable cells to acquire new

突变的 TP53 与 BCAR1 相互作用，促进癌细胞侵袭,British Journal of Cancer - X-MOL

TP53 BCAR1 British Journal of Cancer XMOL

R273C and R273H mutants alter p53 chromatin binding capacity in the ...

R273C and R273H mutants alter p53 chromatin binding capacity in the

Frontiers | Deficient or R273H and R248W Mutations of p53 Promote ...

Frontiers Deficient or R273H and R248W Mutations of p53 Promote

Dysfunction of the TP53 tumor suppressor gene in lymphoid malignancies ...

Dysfunction of the TP53 tumor suppressor gene in lymphoid malignancies

Frontiers | Correction: Deficient or R273H and R248W mutations of p53 ...

Frontiers Correction Deficient or R273H and R248W mutations of p53

Structure du mutant p53 R273H jaune PDB 2BIM superpos avec la

Frame-shift mediated reduction of gain-of-function p53 R273H and ...

Frameshift mediated reduction of gainoffunction p53 R273H and

R27a is downregulated by p53 R273H mutant a H1299 cells with

Distinct functions of wild-type and R273H mutant Δ133p53α ...

Distinct functions of wildtype and R273H mutant 133p53

Frontiers | Oligomerization of Mutant p53 R273H is not Required for ...

Frontiers Oligomerization of Mutant p53 R273H is not Required for

TP53 missense–specific transcriptional plasticity drives resistance ...

TP53 missensespecific transcriptional plasticity drives resistance

p53 R273H mutant overexpression attenuates the induction of NQO1 and

TP53 mutational spectrum in 942 GC patients (a) and TP53 R175H mutation ...

TP53 mutational spectrum in 942 GC patients a and TP53 R175H mutation

Frontiers | Oligomerization of Mutant p53 R273H is not Required for ...

Frontiers Oligomerization of Mutant p53 R273H is not Required for

| R273H-dual mtp53 mutants destabilize oligomerization of mtp53 R273H ...

R273Hdual mtp53 mutants destabilize oligomerization of mtp53 R273H

TP53 missense–specific transcriptional plasticity drives resistance ...

TP53 missensespecific transcriptional plasticity drives resistance

In a p53-null background, R273C and R273H p53 mutants abrogate ...

In a p53null background R273C and R273H p53 mutants abrogate

Wtp53 and R273H mutant bind to CTGCAG tracts in the chromatin context ...

Wtp53 and R273H mutant bind to CTGCAG tracts in the chromatin context

In the presence of wt-p53, R273C and R273H mutants differentially ...

In the presence of wtp53 R273C and R273H mutants differentially

CRISPR-mediated ablation of TP53 and EGFR mutations enhances gefitinib ...

CRISPRmediated ablation of TP53 and EGFR mutations enhances gefitinib

Frontiers | Deficient or R273H and R248W Mutations of p53 Promote ...

Frontiers Deficient or R273H and R248W Mutations of p53 Promote

Model for mutant R273H p53 PARP1 and MCM27 on replicating DNA

Mutants TP53 p.R273H and p.R273C but not p.R273G Enhance Cancer Cell ...

Mutants TP53 pR273H and pR273C but not pR273G Enhance Cancer Cell

R273H promotes invasion and migration in HHUA cells. The p53 rescue ...

R273H promotes invasion and migration in HHUA cells The p53 rescue

Frontiers | Oligomerization of Mutant p53 R273H is not Required for ...

Frontiers Oligomerization of Mutant p53 R273H is not Required for

Frontiers | Oligomerization of Mutant p53 R273H is not Required for ...

Frontiers Oligomerization of Mutant p53 R273H is not Required for

TP53 p.R273H Reference Standard_诊断试剂_南京科佰生物科技有限公司

TP53 pR273H Reference Standard

P53：进化了8亿年的抑癌基因-CSDN博客

P538CSDN

The difference in the EBE contribution of R273H-CmQA-p53 and ...

The difference in the EBE contribution of R273HCmQAp53 and

Figure S1 TP53(R273H) mutation induces a malignant phenotype in HCT116 ...

Figure S1 TP53R273H mutation induces a malignant phenotype in HCT116

m 6 A methylation in the mRNA of p53 R273H A Silencing METTL3

R273 mutants orchestrate a distinct transcriptional signature a SW480

P53-R273H mutation promotes CSC expansion and in vitro and in vivo. a ...

P53R273H mutation promotes CSC expansion and in vitro and in vivo a

The effects of p53-R273H on sensitivity to EGFR-TKIs in NSCLC cells ...

The effects of p53R273H on sensitivity to EGFRTKIs in NSCLC cells

P53-R273H mutation promotes CSC expansion and in vitro and in vivo. a ...

P53R273H mutation promotes CSC expansion and in vitro and in vivo a

An N6-methyladenosine at the transited codon 273 of p53 pre-mRNA ...

An N6methyladenosine at the transited codon 273 of p53 premRNA

Hotspot mutant p53-R273H inhibits KLF6 expression to promote cell ...

Hotspot mutant p53R273H inhibits KLF6 expression to promote cell

p53-R273H promotes NEU1 transcription via activating AKT. (A-C ...

p53R273H promotes NEU1 transcription via activating AKT AC

Figure S1 TP53(R273H) mutation induces a malignant phenotype in HCT116 ...

Figure S1 TP53R273H mutation induces a malignant phenotype in HCT116

Rescue from apoptosis after reconstitution of siRNAinsensitive mutant

Integrin β4 is critical in p53-R273H-NEU1 axis-induced cell migration ...

Integrin 4 is critical in p53R273HNEU1 axisinduced cell migration

Mutant p53R273H regulates AKT and BMF expression in a wide range of

Modulation of proteins involved in the antioxidant response by p53 WT ...

Modulation of proteins involved in the antioxidant response by p53 WT

Human p53-R273H TAD defects reduce oncogenicity of H1299 cells a ...

Human p53R273H TAD defects reduce oncogenicity of H1299 cells a

GOF-R273H-p53 mutation imparts drug resistance. (a) Cell lines with ...

GOFR273Hp53 mutation imparts drug resistance a Cell lines with

A CD24-p53 Axis Contributes to African-American Prostate Cancer ...

A CD24p53 Axis Contributes to AfricanAmerican Prostate Cancer

P53：进化了8亿年的抑癌基因-CSDN博客

P538CSDN

Mutant p53WTsilenced clones retain two alleles for TP53 FISH analysis

Cancer cells harboring mutant p53-R273H are inherently resistant to ...

Cancer cells harboring mutant p53R273H are inherently resistant to

p53-R273H silencing reduces cell survival and intracellular reactive ...

p53R273H silencing reduces cell survival and intracellular reactive

p53-R273H promotes cancer cell migration via upregulation of ...

p53R273H promotes cancer cell migration via upregulation of

Mutant p53R273H regulates PI3KAKT signaling pathway a Knockdown of

p53-R273H promotes NEU1 expression. (A) H1299 cells stably expressing ...

p53R273H promotes NEU1 expression A H1299 cells stably expressing

p53-R273H upregulates neuropilin-2 to promote cell mobility and tumor ...

p53R273H upregulates neuropilin2 to promote cell mobility and tumor

The TRIM71-NHL domain interacts with the TA domain of mutant p53-R273H ...

The TRIM71NHL domain interacts with the TA domain of mutant p53R273H

GOFR273Hp53 mutation imparts drug resistance a Cell lines with

p53-R273H promotes NEU1 transcription via activating AKT. (A-C ...

p53R273H promotes NEU1 transcription via activating AKT AC

p53 R273HP309S and MLL4 colocalize at active enhancers and form

Inhibition of glucosylceramide synthase eliminates the oncogenic ...

Inhibition of glucosylceramide synthase eliminates the oncogenic

Depletion of mutant p53R273H induces BMF Knockdown of mutant p53

Inhibition of glucosylceramide synthase eliminates the oncogenic ...

Inhibition of glucosylceramide synthase eliminates the oncogenic

Differential impact of R273C-p53 and R273H-p53 on induction of ...

Differential impact of R273Cp53 and R273Hp53 on induction of

Ectopic expression of DLX2 in H1299 cells inhibits p53-R273H-induced ...

Ectopic expression of DLX2 in H1299 cells inhibits p53R273Hinduced

Cross-talk between mutant p53 and p62/SQSTM1 augments cancer cell ...

Crosstalk between mutant p53 and p62SQSTM1 augments cancer cell

Figure 1 from Proteasome inhibition paradoxically degrades gain-of ...

Figure 1 from Proteasome inhibition paradoxically degrades gainof

Domain architecture of p53 and nomenclature of clones generated via

Ectopic expression of DLX2 in H1299 cells inhibits p53-R273H-induced ...

Ectopic expression of DLX2 in H1299 cells inhibits p53R273Hinduced

An N6-methyladenosine at the transited codon 273 of p53 pre-mRNA ...

An N6methyladenosine at the transited codon 273 of p53 premRNA

Cross-talk between mutant p53 and p62/SQSTM1 augments cancer cell ...

Crosstalk between mutant p53 and p62SQSTM1 augments cancer cell

Cross-talk between mutant p53 and p62/SQSTM1 augments cancer cell ...

Crosstalk between mutant p53 and p62SQSTM1 augments cancer cell

Presence of mutant p53 increases stem cell frequency and is associated ...

Presence of mutant p53 increases stem cell frequency and is associated

Inhibition of glucosylceramide synthase eliminates the oncogenic ...

Inhibition of glucosylceramide synthase eliminates the oncogenic

An N6-methyladenosine at the transited codon 273 of p53 pre-mRNA ...

An N6methyladenosine at the transited codon 273 of p53 premRNA

Figure 3 from Proteasome inhibition paradoxically degrades gain-of ...

Figure 3 from Proteasome inhibition paradoxically degrades gainof

P53-R273H mutation enhances colorectal cancer stemness through ...

P53R273H mutation enhances colorectal cancer stemness through

Full article: Mutant p53 drives cancer chemotherapy resistance due to ...

Full article Mutant p53 drives cancer chemotherapy resistance due to

Mutant p53-R273H suppresses cellular anoikis. (a–b) Endogenous ...

Mutant p53R273H suppresses cellular anoikis ab Endogenous

Thermodynamic resilience of wild-type p53 DNA-binding domain and its ...

Thermodynamic resilience of wildtype p53 DNAbinding domain and its

p53-R273H overexpression differently modulates cyclin D1 expression in ...

p53R273H overexpression differently modulates cyclin D1 expression in

p53-R273H Sustains ROS, Pro-Inflammatory Cytokine Release and mTOR ...

p53R273H Sustains ROS ProInflammatory Cytokine Release and mTOR

Ceramide restores wt p53 expression in cells carrying heterozygous

Comparison of OxPhos function in H 2 O 2 treated HCT116 TP53−/− cells ...

Comparison of OxPhos function in H 2 O 2 treated HCT116 TP53 cells

P53-R273H mutation enhances colorectal cancer stemness through ...

P53R273H mutation enhances colorectal cancer stemness through

P53R273H binds gene regulatory elements and augments transcription a

不是所有的TP53基因突变都一样，R273H突变用PD-1疗效好，Y220C突变有临床试验靶向药免费用！ - 知乎

TP53R273HPD1Y220C

Frontiers | Mutant p53K120R expression enables a partial capacity to ...

Frontiers Mutant p53K120R expression enables a partial capacity to

Presence of mutant p53 increases stem cell frequency and is associated ...

Presence of mutant p53 increases stem cell frequency and is associated

Stereo view of the R273-related mutants superposed on the wt core ...

Stereo view of the R273related mutants superposed on the wt core

Figure 2 from Proteasome inhibition paradoxically degrades gain-of ...

Figure 2 from Proteasome inhibition paradoxically degrades gainof

Knockdown of endogenous p53-R273H contact mutant, but not R175H ...

Knockdown of endogenous p53R273H contact mutant but not R175H

Frontiers | Proteasome inhibition paradoxically degrades gain-of ...

Frontiers Proteasome inhibition paradoxically degrades gainof

P53 regulates induction of autophagy in R273HP53 cells a Immunoblot

Differential impact of R273C-p53 and R273H-p53 on induction of ...

Differential impact of R273Cp53 and R273Hp53 on induction of

R27a is a transcriptional target of p53 273H a Schematic

Oncology Reports

Oncology Reports

Effect of CQ on proliferation of R273H-P53 harboring NSCLC cells. A ...

Effect of CQ on proliferation of R273HP53 harboring NSCLC cells A

Sensitivity of VHL mutant kidney cancers to HIF2 inhibitors does not ...

Sensitivity of VHL mutant kidney cancers to HIF2 inhibitors does not

p53-R273H Sustains ROS, Pro-Inflammatory Cytokine Release and mTOR ...

p53R273H Sustains ROS ProInflammatory Cytokine Release and mTOR

TP53 Gene Structure

贝林妥单抗 TP53

TP53 Gene Cancer

Chromosome 17 TP53

TP53 Gene Domains

TP53 Li-Fraumeni Syndrome

Leukemia Pathophysiology

CHEK2 Gene Mutation

TP53 Gene Karyotype

Fonction Gène TP53

TP53 Phosphorylation

P53 in Cell Cycle

TP53 DNA-binding Domain

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