Supf

Strategy for the construction of a modified supF gene containing a

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SupF assay results a Mutation frequency obtained by overexpressing

Replication Fidelity of the supF Gene Integrated in the Thymidine

Human shuttle vector pSP189 The plasmid contains the bacterial SupF

The supF mutant frequency in U2OS cells transfected with plasmid DNA

Sequence analysis of deletion mutations generated in the supF gene in

Power functions for SupF and AveF tests for testing the null of 1

Plating efficiency a of amHE258 in SupD b SupE and SupF cell lines

Frequencies of supF mutants in a shuttle vector containing a dG b

Binding of AG1O to the supF gene target To assay for triplex

Sequence analysis of mutations generated by psoAG10 in the supF

Effects of TRIP13 deficiency in TLS assays a Schematic of the SupF

An example of SUPF score and rating calculation Download Scientific

Mutation frequencies determined using either the lacI supF or cII

Human shuttle vector pSP189 The plasmid contains the bacterial SupF

JSRV supF is infectious in vitro a Schematic diagram of the JSRV

Presence of DNA coding for SV40 Tantigen in variant supF mutants

PARP10 is required for translesion DNA synthesis A SupF mutagenesis

Replication Fidelity of the supF Gene Integrated in the Thymidine

Restriction analysis of supF mutants The pZ189 DNA from nine

Mutation frequencies and spectra affecting supF gene function in

Visualization of termination fragments of the supF gene using

The supF tRNA gene sequence in each supF mutant that contained a

Distribution of spontaneous mutations detected in the supF gene of

Sequence analysis of mutations generated by psoAG10 in the supF

Restriction analysis of supF mutants The pZ189 DNA from nine

Distribution of the crotonaldehydeinduced base substitutions in supF

Targeted mutagenesis in the chromosomal supF gene using pcPNAs A

Mutation spectra generated by UVC 1000 Jm 2 of SupF gene in T24

supF mutation spectra where the tRNA nucleotide sequence for the NT

Targeted mutagenesis in the chromosomal supF gene using pcPNAs A

Restriction analysis of supF mutants The pZ189 DNA from nine

Confirmation of the presence of a wildtype supF gene in plasmids with

Types of acetaldehydeinduced tandem base substitution in the supF gene

Mutation frequency of SupF gene in T24 cells Download Table

Sequenced mutations arising in the supF SV after replication in human

2 Weightings of dimensions and categories of SUPF based on the

supF mutation spectra where the tRNA nucleotide sequence for the NT

Spectrum of MDAinduced base substitutions within the supF reporter

Mutagenesis of the supF Gene of pSP189 Replicating in AD293 Cells

Replication Fidelity of the supF Gene Integrated in the Thymidine

SupF forward mutation assay using CAAtreated plasmid pMY189 in

Deletions and rearrangements with endpoints in the supF gene and

Restriction analysis of supF mutants The pZ189 DNA from nine

Performance of the supF mutagenicity nextgeneration sequencing NGS

Schematic diagram of the mutation spectra in the supF gene of the

Performance of the supF mutagenicity nextgeneration sequencing NGS

The distribution of 76 UVinduced substitution mutations in the supF

Determination of mutations generated by cisplatin in the supF reporter

Distribution of 4OHEQinduced base substitutions in supF gene The

SupF test of no structural break in time dynamics Note xaxis Time

SupF assay results a Mutation frequency obtained by overexpressing

supF mutation frequencies in pHOS1 by transientreplication assay

WRN depletion significantly increases the supF mutant frequencies for

Overall distribution of the substitution mutations detected in the supF

Integration reaction with a supF containing substrate to investigate

The distribution of 76 UVinduced substitution mutations in the supF

Mutagenesis of the supF Gene by Stereoisomers of 1234Diepoxybutane

Mutation frequencies in the supF gene of plasmid pMY189 replicated in

Classification of substituted bases in the supF gene Download Table

Deletions and rearrangements with endpoints in the supF gene and

Replication Fidelity of the supF Gene Integrated in the Thymidine

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Replication Fidelity of the supF Gene Integrated in the Thymidine

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Figure 2

Mouse Mammary Tumor Virus Carrying a Bacterial supFGene Has WildType

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Plasmid substrates used in the DSB repair assays A supF20 reverts to

MCF 1dr supF proviruses integrated upstream of cmyc Diagrammatic

Mouse Mammary Tumor Virus Carrying a Bacterial supFGene Has WildType

Untargeted Mutation Triggered by Ribonucleoside Embedded in DNA

Plasmid substrates used in the DSB repair assays A supF20 reverts to

Schematic representation of the construction of the supFcontaining

Southern blots of recombinants containing integrated pSupF1 sequences

A The scheme of a restriction enzyme protection assay to detect

AND Logic Based on Suppressor tRNAs Enables Stringent Control of

Highresolution functional mapping of a cloned gene by genetic

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The presence of functional Rev1 determines the types of mutations near

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Development of a supFbased mutationdetection system in the extreme

Mutation spectrum of a dG b rG c 8oxorG and d 8oxodG in

Mutation spectra depicting single base and tandem substitutions in the

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Schematic representation of the construction of the supFcontaining

MCF 1dr supF proviruses integrated upstream of cmyc Diagrammatic

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New indicator Escherichia coli strain for rapid and accurate detection

Homologous recombination assay for substrates containing one

Effects of Exonuclease Activity and Nucleotide Selectivity of the

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Figure 1 from Comparison of mutagenic potentials and mutation spectra

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