Snf2h

SIRT6 Recruits SNF2H to DNA Break Sites Preventing Genomic Instability

Accumulation of SNF2h at DNA breaks requires NuMA a Accumulation of

SNF2h and ACF function as dimers of ATPasesa Schematic of nucleosome

In Situ Hybridization Analysis of SNF2L and SNF2H during Ovary

Coordinated asymmetric actions of SNF2h protomers on a nucleosome a

Sitedirected photocrosslinking strategy used to explore SNF2h

The extent of SNF2H knockdown correlates with reduction of HSV1

SNF2H is highly expressed in HCC A Western blot assays showed that

Purification of SNF2H and BRG1 Both proteins were tagged with the FLAG

Schematic prediction of SNF2H SANT domain bound to DNA PDB ID6NE3

Sitedirected photocrosslinking strategy used to explore SNF2h

a Schematic representing the Cremediated deletion of Snf2h in the

Mechanisms of chromatin remodeling by the human Snf2type ATPase SNF2H

In Situ Hybridization Analysis of SNF2L and SNF2H during Ovary

Frontiers Snf2h Drives Chromatin Remodeling to Prime Upper Layer

SNF2h and ACF function as dimers of ATPasesa Schematic of nucleosome

Snf2h mediates chromatin transitions through linker histone H1

Visualization of SNF2h bound to the nucleosome in the presence of

Sitedirected photocrosslinking strategy used to explore SNF2h

Snf2h loss results in intrinsic GNP cell death without altering Shh

Snf2h is necessary for proper chromatin folding a Transmission

Snf2h and Snf2l are dynamically regulated in the developing cerebellum

SNF2H can remodel a nucleosome array A a schematic diagram of the 5 S

a Schematic representing the Cremediated deletion of Snf2h in the

SNF2h depletion reduces chromatin remodeling histone deacetylation

SNF2H organizes nucleosomes at CTCF binding sites AC Mono

SNF2H binding to origins is inhibited by Cdt1 silencing and enhanced by

Snf2h is necessary for proper chromatin folding a Transmission

Sitedirected photocrosslinking strategy used to explore SNF2h

Snf2h loss alters PC maturation a Snf2h red and Calbindin green

Expression of Snf2h and initial analysis of the Snf2h lens conditional

SNF2H organizes nucleosomes at CTCF binding sites AC Mono

Decreased SNF2H levels result in reduced HSV1 replication Download

Visualization of SNF2h bound to the nucleosome in the presence of

SNF2H promotes HCC cell proliferation in vitro A SNF2H expression in

Purification of SNF2H and BRG1 Both proteins were tagged with the FLAG

Frontiers Snf2h Drives Chromatin Remodeling to Prime Upper Layer

Chromatin remodeling enzyme Snf2h regulates embryonic lens

SNF2H organizes nucleosomes at CTCF binding sites AC Mono

SNF2H and RNF20 enable specifically heterochromatic relaxation after

SNF2H does not alter the topology of circular chromatin Labeled pUC19

SNF2H and RNF20 enable specifically heterochromatic relaxation after

The extent of SNF2H knockdown correlates with the reduction of ICP0

BRG1 and SNF2h generate different remodeled products A 202bp

SNF2L and SNF2H expression in human tissues The same antibodies as in

SNF2h slides histone cores with asymmetric acidic patch mutations off

The chromatin remodeler Snf2h is essential for oocyte meiotic cell

Altered cell cycle kinetics within Snf2h cKO neural progenitors A

A Native electrophoresis of SNF2H remodeled products Nucleosomes

Depletion of SNF2H affects the transcription of many genes regulated by

Targeted disruption of the mouse SNF2h gene A Strategies for

siRNA knockdown of SNF2h and INO80 subunits reduce virus de novo

RNF20SNF2H Pathway of Chromatin Relaxation in DNA DoubleStrand Break

PDF Functionalized grapheneoxide grids enable highresolution cryo

Functionalized grapheneoxide grids enable highresolution cryoEM

A NucleotideDriven Switch Regulates Flanking DNA Length Sensing by a

Structure of Snf2related enzymes SNF2H Snf2 and Chd1 bound to

Functionalized grapheneoxide grids enable highresolution cryoEM

Human ACF1 Alters the Remodeling Strategy of SNF2h Journal of

Distinct Strategies to Make Nucleosomal DNA Accessible Molecular Cell

Human ACF1 Alters the Remodeling Strategy of SNF2h Journal of

Functionalized grapheneoxide grids enable highresolution cryoEM

Human ACF1 Alters the Remodeling Strategy of SNF2h Journal of

CryoEM structures of remodelernucleosome intermediates suggest

A model of SNF2hmediated chromatin regulation based on results of this

Functional Differences between the Human ATPdependent Nucleosome

Functionalized grapheneoxide grids enable highresolution cryoEM

Distinct Strategies to Make Nucleosomal DNA Accessible Molecular Cell

Confocal images of Snf2HGFP GFPSnf2L and GFPSnf2L13 in U2OS

A basic motif anchoring ISWI to nucleosome acidic patch regulates

SMARCA5SNF2H Rabbit antiHuman Mouse Rat Clone S059D5 Novus

Mammalian ISWI and SWISNF selectively mediate binding of distinct

Chromatin Remodeler Sucrose Nonfermenting 2 Homolog SNF2H Is

RCSB PDB 8V7L CryoEM structure of singlybound SNF2hnucleosome

PFN1 increases the stalling of stressed DNA replication forks a b

CryoEM structures of remodelernucleosome intermediates suggest

Functionalized grapheneoxide grids enable highresolution cryoEM

Frontiers Impaired SNF2L Chromatin Remodeling Prolongs Accessibility

RCSB PDB 8V7L CryoEM structure of singlybound SNF2hnucleosome

Distinct Strategies to Make Nucleosomal DNA Accessible Molecular Cell

A basic motif anchoring ISWI to nucleosome acidic patch regulates

A Tissuespecific Naturally Occurring Human SNF2L Variant Inactivates

RCSB PDB 8V7L CryoEM structure of singlybound SNF2hnucleosome

Mapping of the BRG1and SNF2hremodeled products A BRG1and

Sequence and functional differences in the ATPase domains of CHD3 and

Mammalian ISWI and SWISNF selectively mediate binding of distinct

WSTF regulates the function of H2AX via a novel tyrosine kinase

SNF2HACF1 and RNF20 remain essential for heterochromatic relaxation

Functional Differences between the Human ATPdependent Nucleosome

Histone dynamics play a critical role in SNF2hmediated nucleosome

Sequence and functional differences in the ATPase domains of CHD3 and

NuMA interacts with SNF2h a Confocal images of SNF2hGFP and

PDF Maintaining chromosome and genome stability by the RPARNF20

RCSB PDB 6NE3 CryoEM structure of singlybound SNF2hnucleosome

Snf2HGFP rescues the Snf2HKO phenotype A to verify that the sirNA

SNF2L but not SNF2H is reduced in malignant melanoma A Primer sets

The nucleosomal acidic patch relieves autoinhibition by the ISWI

Mammalian ISWI and SWISNF selectively mediate binding of distinct

Sequence and functional differences in the ATPase domains of CHD3 and

RCSB PDB 8V4Y CryoEM structure of singlybound SNF2hnucleosome

Sequence and functional differences in the ATPase domains of CHD3 and

Full article Binding kinetics of human ISWI chromatinremodelers to

Maintaining chromosome and genome stability by the RPARNF20SNF2H

The RPARNF20SNF2H cascade promotes proper chromosome segregation and

Functional Differences between the Human ATPdependent Nucleosome

Chromatin Remodelers

Chromatin Remodeling

Chromatin Remodeling Complex

Snf2h Histone Modification

Chromatin Instability

Snf2h Review

Snf2h Transcription

Iswi Chromatin Remodeling

Smarca5

Photocrosslinking

Nucleosome

Snf2h Transcription Repression

Chromatin Remodeling Protein

Iswi Chromatin Remodeling Complex

Chromatin Remodeler

Snf2h Complex

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