Sim1

Creation of a Sim1 allele expressing TaulacZ A Schematic

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Pharmacogenetic silencing and activation of Sim1 neurons modulate food

Sim1 Mutant Presumptive PVNSON Cells Do Become Neurons A D and G

AdenoviralMediated Modulation of Sim1 Expression in the

SIM1 and SIM2 are nuclear proteins in human embryonic kidney cells A

Dnmt3a in Sim1 Neurons Is Necessary for Normal Energy Homeostasis

Immunofluorescence and quantitation of SIM1 neurons in PVN and SON of

Generation and characterization of Sim1 Cre and Sim1 taulacZ mice

SIM1 and SIM2 are nuclear proteins in human embryonic kidney cells A

Sim2 Is a Downstream Gene of Sim1 Sim1 A A and Sim2 B B

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Disruption of GlucagonLike Peptide 1 Signaling in Sim1 Neurons Reduces

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SIM1 and SIM2 are nuclear proteins in human embryonic kidney cells A

A Diagram of wildtype SIM1 locus top and SIM1 locus with its

Comparison of Sim1 Sim2 and Brn2 Gene Expression in the Newborn

Evaluation of SIM1 derivatives for structural activity relationship

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In vitro interactions of SIM1 A dimerization of SIM1 with ARNT

Model for SIM1 Action in Melanocortin Signaling Pathway See text for

Identification of Sim1 transcription start site by 5RACE analysis A

Identification of a single nucleotide substitution in the Sim1 gene in

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Expression studies of SIM1 A RTqPCR expression of SIM1 along the

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Sim1 Is a Novel Regulator in the Differentiation of Mouse Dorsal Raphe

Postnatal Sim1 Deficiency Causes Hyperphagic Obesity and Reduced Mc4r

Frontiers Melanocortin 4 receptor signaling in Sim1 neurons permits

Structurebased designed trivalent PROTAC SIM1 is the most potent

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Sim1 expression in wildtype and Sim1 mutant mouse specimens at E165

Impact of Sim1 on protein abundance of early and late markers of the

Targeted inactivation of mouse Sim1 gene using CreloxP strategy A

The SIM1 and SIM2 mutations disrupt rhTRIM5α localization to nuclear ...

The SIM1 and SIM2 mutations disrupt rhTRIM5 localization to nuclear

Sim1 Heterozygous Mice Fail to Activate PVN Neurons in Response to MTII

Model for SIM1 Action in Melanocortin Signaling Pathway See text for

SIM1 and SIM2 are nuclear proteins in human embryonic kidney cells A

Sim1 gene dosage modulates the homeostatic feeding response to

Histology of BAT and WAT of Sim1 and Sim1 mice A and B

Disruption of GlucagonLike Peptide 1 Signaling in Sim1 Neurons Reduces

SIM1 and SIM2 are nuclear proteins in human embryonic kidney cells A

Recombination of floxed Sim1 allele with EIIaCre ABSim1 heterozygous

Generation of Sim1 transgenic mice A Map of human SIM1 BAC clone B

Histology of BAT and WAT of Sim1 and Sim1 mice A and B

Recombination of floxed Sim1 allele with EIIaCre ABSim1 heterozygous

Genetic variation in the SIM1 locus is associated with erectile

ChR2 and iC expression in PVH Sim1 neurons of Sim1Cre and

Dnmt3a in Sim1 Neurons Is Necessary for Normal Energy Homeostasis

AdenoviralMediated Modulation of Sim1 Expression in the

Ablation of Sim1 neurons causes hyperphagic obesity A Growth curves

Loss of InsR signals in Sim1 neurons did not lead to changes in stress

Histology of BAT and WAT of Sim1 and Sim1 mice A and B

Generation of Sim1 transgenic mice A Map of human SIM1 BAC clone B

Glutamate Mediates the Function of Melanocortin Receptor 4 on Sim1

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Responsiveness of PVH Sim1 neurons to acute stress a b A diagram

Dnmt3a in Sim1 Neurons Is Necessary for Normal Energy Homeostasis

Histology of BAT and WAT of Sim1 and Sim1 mice A and B

Dnmt3a in Sim1 Neurons Is Necessary for Normal Energy Homeostasis

Sim1 Expression in Sim2 Mutant Newborn Brain Is Not Reduced Expression

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Metabolic phenotypes of Sim1 mutant mice a Both male and female Sim1

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Sim1 Mice Exhibit Reduced mRNA Expression of Download

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AdenoviralMediated Modulation of Sim1 Expression in the

The Sim1 testing environment Download Scientific Diagram

Sim1 gene dosage modulates the homeostatic feeding response to

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In this model loss of Sim1 neurons in the PVN leads to increased Sim1

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Sim1 Expression in Sim2 Mutant Newborn Brain Is Not Reduced Expression

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Ablation of Sim1 neurons reduces activity Total and ambulatory

Unbiased stereologic counting of PVN cells in germline Sim1

Sim1 gene dosage modulates the homeostatic feeding response to

Genomic and epigenetic annotations of the SIM1 locus A A University

AdenoviralMediated Modulation of Sim1 Expression in the

SIM1 inhibits binding of the AHRARNT heterodimer to the XRE A in

The performance of four methods a TPR of Sim1 dataset b FDR of the

Ablation of Sim1 neurons reduces resting energy expenditure body and

Genetic variation in the SIM1 locus is associated with erectile

Structural Models for the Dynamic Effects of LossofFunction Variants

scRNAseq analysis of Sim1Cre cells reveal characteristics of PVH

MTEG and MTT development affected by Sim1Sim2 gene dosage E185

Sim1Cre Transgenic Mice Download Scientific Diagram

Singleminded 1 Sim1Cre Rosa mice express membranebound enhanced

Generation of an ab initio hybrid model for SIM1 A Previously

Generation and identification of Sim1Puro cell line a Red

Conformational change of LoopSIM1 upon binding to the E2SUMOD donor a

Sim1expressing neurons in the paraventricular nucleus are ciliated a

Structural Models for the Dynamic Effects of LossofFunction Variants

Development of neuroendocrine lineages requires the bHLHPAS

Expression constructs of SIM1 SIM2 ARNT and AHR The basic region is

JCI Rare variants in singleminded 1 SIM1 are associated with

A Sim1associated ASHCE represents an enhancer activity a

Expression of Sim1 Lhx6 Otp or Tbr1 in the developing mouse

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Sim1expressing cells illuminate the origin and course of migration of

Expression constructs of SIM1 SIM2 ARNT and AHR The basic region is

PAS interactions distal to the core binding sites are associated with

Deletion of the Bdnf Gene in the PVH Using the Sim1Cre Transgene A

JCI Rare variants in singleminded 1 SIM1 are associated with

Several upregulated genes display expression patterns correlating with

Sim1expressing neurons in the paraventricular nucleus are ciliated a

How genetics influences our body weight beyond genes Hale Plus Hearty

PDF Allocation of Paraventricular and Supraoptic Neurons Requires

JCI Rare variants in singleminded 1 SIM1 are associated with

Sim1Creinduced KD of Glp1r within the PVN A Genetic strategy to

Sim1Cre and Wfs1CreER Mice Give Genetic Access to L2 Stellate and

Leptin Receptor Signaling in Sim1Expressing Neurons Regulates Body

Sim1expressing cells illuminate the origin and course of migration of

Sim1Cre Glp1r KD attenuates cardiovascular responses to acute

Mammillary body neurons survive until the end of gestation in Sim1Sim2

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