Rala Ralb

The RAL Enigma Distinct Roles of RALA and RALB in Cancer

Genetic Deletion of RALA and RALB Small GTPases Reveals Redundant

RalA and RalB are required for EC tubulogenesis in 3D matrices A EC

Comparison of human RALA and RALB sequences Sequences were aligned

Figure 2 from The Rasrelated small GTPases RalA and RalB regulate

RalA and RalB Proteins Are Ubiquitinated GTPases and Ubiquitinated

Loss of Ecadherin function induces downregulation of RalA and RalB in

Effects of KRAS signaling on RALA and RALB expression and activity

RalA and RalB relocalization to depolarized mitochondria occurs

Effect of RalA and RalB siRNA treatment on FLAGAT 1 R internalization

Figure 3 from Genetic Deletion of RALA and RALB Small GTPases Reveals

RalB rather than RalA mediates SDF1 induced MM cell migration A

CycD1 modulates RalA and RalB activity a RalBP beads were used for

RalA and RalB regulate cytotoxicity in YTS cells A and B The

RalA and RalB negatively regulate TBK1 activity A shScramble and

RalA and RalB differentially regulate development of epithelial tight

RalA and RalB Function as the Critical GTP Sensors for GTPDependent

Genetic Deletion of RALA and RALB Small GTPases Reveals Redundant

RalA and RalB are required for EC tubulogenesis in 3D matrices A EC

hGH stimulates the formation of GTPbound RalA and RalB in NIH3T3

Full activation of RalA and RalB by hGH requires both JAK2 and cSrc

RalA and RalB differentially regulate development of epithelial tight

Genetic Deletion of RALA and RALB Small GTPases Reveals Redundant

RalA and RalB are required for EC tubulogenesis in 3D matrices A EC

RasRelated Small GTPases RalA and RalB Regulate Cellular Survival

$Endogenous RalA and RalB in platelet particulate fraction interact with ...$

Endogenous RalA and RalB in platelet particulate fraction interact with

RalA and RalB regulate cytotoxicity in YTS cells A and B The

PDF RalA and RalB Proteins Are Ubiquitinated GTPases and

RalA and RalB regulate cytotoxicity in YTS cells A and B The

PDF RalA and RalB differentially regulate development of epithelial

RalA and RalB Proteins Are Ubiquitinated GTPases and Ubiquitinated

RalA and RalB localize to lytic granules A YTS cells were incubated

Fulllength and Cterminally truncated RalA and RalB bind CaM in the

Full article Differential involvement of RalA and RalB in colorectal

Fulllength and Cterminally truncated RalA and RalB bind CaM in the

hGH stimulates the formation of GTPbound RalA and RalB in NIH3T3

RalGAPβ deficiency increases RalA and RalB activity and enhances ...

RalGAP deficiency increases RalA and RalB activity and enhances

Effects of WT and constitutively active RalA and RalB on p27

Divergent Roles for RalA and RalB in Malignant Growth of Human

Calmodulin Binds RalA and RalB and Is Required for the Thrombininduced

PDF Distinct roles of RalA and RalB in the progression of cytokinesis

RalA and RalB Function as the Critical GTP Sensors for GTPDependent

Farnesylated and geranylgeranylated RalA and RalB are equivalent in

PDF RalA and RalB function as the critical GTP sensors for GTP

CycD1 modulates RalA and RalB activity a RalBP beads were used for

RalGAP deficiency increases RalA and RalB activity and enhances

Calmodulin Binds RalA and RalB and Is Required for the Thrombininduced

Longterm loss of RalA in SCs and constitutive lack of RalB leads to

Divergent Roles for RalA and RalB in Malignant Growth of Human

RasRelated Small GTPases RalA and RalB Regulate Cellular Survival

RalA and RalB Function as the Critical GTP Sensors for GTPDependent

PDF Differential involvement of RalA and RalB in colorectal cancer

Divergent Roles for RalA and RalB in Malignant Growth of Human

RALA supports while RALB opposes in vitro measures of aggressive

RasRelated Small GTPases RalA and RalB Regulate Cellular Survival

Effects of WT and constitutively active RalA and RalB on p27

PDF Coding sequences of human ralA and ralB cDNAs

PDF RalA and RalB relocalization to depolarized mitochondria depends

RalA and RalB differentially regulate development of epithelial tight

Both RalA and RalB are recruited to depolarized mitochondria A HeLa

RalA and RalB differentially regulate development of epithelial tight

RalA and RalB Function as the Critical GTP Sensors for GTPDependent

Calmodulin Binds RalA and RalB and Is Required for the Thrombininduced

Loss of RalA in SCs in RalB animals leads to mildly impaired motor

RALA is elevated in TNBC and is prognostic of overall survival in

RalB and the Exocyst Mediate the Cellular Starvation Response by Direct

Activation of RalA is critical for Rasinduced tumorigenesis of human

Rala and Ralb Antagonistic Relatives in Cancer Cell Migration DocsLib

C3bot and Ral form a stable complex A Influence of RalA RalB and

Interaction of RalA with the exocyst complex is crucial for SC process

Effect of RalA to RalBP1 binding on the function of RalA in PC3

Suppression of RalA expression by shRNA induces invasive properties in

Schematic illustration of the main functions of Rab Arf and RalB small

Effects of depletion of KRas RalA and RalB on cell cycle progression

Depletion of KRas RalA and RalB increases p53 protein stability A

Depletion of RalA induces accumulation of binucleate cells whereas

RalB regulates dissemination of TGFtreated cells A RalB silencing

Effects of depletion of KRas RalA and RalB on cell cycle

Activation of RalA is critical for Rasinduced tumorigenesis of human

Effects of depletion of KRas RalA and RalB on apoptosis H460 and

Effects of depletion of KRas RalA and RalB on cell cycle progression

RalB GTPase-Mediated Activation of the IκB Family Kinase TBK1 Couples ...

RalB GTPaseMediated Activation of the IB Family Kinase TBK1 Couples

RalGDS induces RalA activation and WPB exocytosis A Activation of

Membrane extraction by calmodulin underpins the disparate signalling of

BioEssays Vol 44 No 6

RAL GTPases Biology and Potential as Therapeutic Targets in Cancer

RALA not RALB is protumorigenic in preclinical in vivo models of

Expression and activation of Ral proteins in macrophages A Western

Knockdown of RalAB affects mouse oocyte maturation A Realtime

Electron microscopy of the RalARalB double knockdown cells does not

RALA not RALB is protumorigenic in preclinical in vivo models of

Transcriptional signatures of Ral GTPase are associated with aggressive

Horiuchi Lab Devertment of molecular and cellular biology Institute

Contributions of KRAS and RAL in NonSmallCell Lung Cancer Growth and

Model for RalBregulated vesicular fusion Based on our observations

Inducible expression of RalA72L and of RalB72L in T23 MDCK cell lines

Raldependent stimulation of spontaneous metastatic activity a

Contributions of KRAS and RAL in NonSmallCell Lung Cancer Growth and

Electron microscopy of the RalARalB double knockdown cells does not

Table 1 from Thermodynamic mapping of effector protein interfaces with

HumanMouseRat RalARalB Antibody AF3204 RD Systems

Subcellular localization of RalAB during mouse oocyte meiosis A

Depletion of endogenous Ral by RNAi decreases branching Cortical

The RAL Small G Proteins Are Clinically Relevant Targets in Triple

RALA not RALB is protumorigenic in preclinical in vivo models of

Full article RLIP76 RalBP1

KRAS oncogene substitutions in Korean NSCLC patients Clinical

Expression of the two RAL isoforms in multiple myeloma cells

Abbildung 6 Expression der RALIsoformen in Myelomzellen A

GSTRalA and GSTRalB bind to endogenous CaM from platelet extracts in

Membrane extraction by calmodulin underpins the disparate signalling of

Aberrant Overexpression of the Rgl2 Ral Small GTPasespecific Guanine

GSTRalA and GSTRalB bind to endogenous CaM from platelet extracts in

HumanMouseRat RalARalB Antibody AF3204 by RD Systems Part of Bio

Ral knockdown reduces the invasiveness of MDAMB231 cells A

Rala Rwdins Activities

Rala Mouse

Rala Rwdins

Rala Gene

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