Rad52 Inhibitor

DI03 is a Selective RAD52 Inhibitor Network of Cancer Research

Identification of a Small Molecule Inhibitor of RAD52 by Structure

PDF Identification of a Small Molecule Inhibitor of RAD52 by

Identification of a Small Molecule Inhibitor of RAD52 by Structure

RAD52 Inhibitor 6OHDopa Attenuated HR and SSA in BRCA12Deficient

RAD52 as a Potential Target for Synthetic LethalityBased Anticancer

Models of SmallMolecule Inhibition of RAD52 A Models of 6OHdopa

Emerging Roles of RAD52 in Genome Maintenance

RAD52 Adjusts Repair of SingleStrand Breaks via Reducing DNADamage

RAD52 Breakthrough Offers Hope for Targeted Cancer Therapy IMAGE Magazine

Multiple roles of RAD52 at perturbed replication forks Model

Physiological and Pathological Roles of RAD52 at DNA Replication Forks

Identification of RAD52 Inhibitors by HighThroughput Screening A

Human RAD52 stimulates the RAD51mediated homology search Life

Proposed binding regions of the RAD52 inhibitors A 63 and B 64

Emerging Roles of RAD52 in Genome Maintenance

Multiple roles of RAD52 during DNA replication and repair A RAD52

Physiological and Pathological Roles of RAD52 at DNA Replication Forks

Current Understanding of RAD52 Functions Fundamental and Therapeutic

RAD52 as a Potential Target for Synthetic LethalityBased Anticancer

Targeting BRCA1 and BRCA2deficient cells with RAD52 small molecule

RAD52 and BRCA2 inhibit POLθ DNA synthesis by distinct mechanisms a ...

RAD52 and BRCA2 inhibit POL DNA synthesis by distinct mechanisms a

RAD52 Adjusts Repair of SingleStrand Breaks via Reducing DNADamage

RAD52 Functions in Homologous Recombination and Its Importance on

S cerevisiae Rad52 functions as a homodecamer A Schematic

RAD52 Adjusts Repair of SingleStrand Breaks via Reducing DNADamage

Targeting BRCA1 and BRCA2deficient cells with RAD52 small molecule

Reappearance from Obscurity Mammalian Rad52 in Homologous Recombination

Simultaneous Targeting of PARP1 and RAD52 Triggers Dual Synthetic

DNA repair protein RAD52 is required for protecting Gquadruplexes in

Localization and dynamic relocalization of mammalian Rad52 during the

RAD52 Facilitates Mitotic DNA Synthesis Following Replication Stress

Structural Basis of HomologyDirected DNA Repair Mediated by RAD52

Rad52 Is Required for Fork Restart after Prolonged Exposure of Cells to

In the absence of both RAD52 and BRCA2 ssDNARAD51 interactions are

DNA repair by Rad52 liquid droplets PMC

The Rad51 nucleoprotein complex is the most effective inhibitor of

Human RAD52 Captures and Holds DNA Strands Increases DNA Flexibility

RAD52 promotes stalled fork degradation in BRCA2defective cells a

RAD52 domains and multimerization a Domain schematic of fulllength

Structural Basis of HomologyDirected DNA Repair Mediated by RAD52

The cryoEM structure of fulllength RAD52 protein contains an

Replication Stress Response Links RAD52 to Protecting Common Fragile Sites

Proposed models for the role of RAD52 in repair of DSBs containing DNA

DNA repair protein RAD52 is required for protecting Gquadruplexes in

Targeting BRCA1 and BRCA2deficient cells with RAD52 small molecule

RAD52 Adjusts Repair of SingleStrand Breaks via Reducing DNADamage

Models of SmallMolecule Inhibition of RAD52 A Models of 6OHdopa

RAD52 Adjusts Repair of SingleStrand Breaks via Reducing DNADamage

Specificity of the new synthetic compounds towards RAD52 versus RPA is

Rad52 inhibits X DNAbased strand exchange via intramolecular

RAD52 Facilitates Mitotic DNA Synthesis Following Replication Stress

RAD52 domains and multimerization a Domain schematic of fulllength

Synthetic lethality by targeting the RAD52 gene The resolution of the

Rad52 sorts and stacks Rad51 at the DNA junction to promote homologous

Characterization of the biochemical activities of RAD52 WT RAD52

The DNAbinding domain of RAD52 is required for inhibition of

2D diagrams of the interactions between RAD52 and the four candidate

Modeling of the interaction between RAD52 DNA binding domain 1 and

Subcellular localization of the WT and S346X RAD52 proteins tagged with

DNA repair by Rad52 liquid droplets PMC

Rad52 sorts and stacks Rad51 at the DNA junction to promote homologous

Mammalian RAD52 Functions in BreakInduced Replication Repair of

RAD52 resolves transcriptionreplication conflicts to mitigate Rloop

RAD52 S346X is dysfunctional in promoting SSA A The domain map of

Human RAD52 a novel player in DNA repair in cancer and

Rad52 protein expression was inhibited by curcumin following DNA

Small molecule inhibitors targeting RAD52 with their respective

Nonrecombinogenic roles for Rad52 in translesion synthesis during DNA

Transcriptomics and Proteomics Analysis of the Liver of RAD52 Knockout Mice

Coordinated response of mammalian Rad51 and Rad52 to DNA damage EMBO

The effect of R55H D149E and G59R on the structure of RAD52

DNA repair protein RAD52 is required for protecting Gquadruplexes in

The DNA Binding Preference of RAD52 and RAD59 Proteins Journal of

Mammalian RAD52 Functions in BreakInduced Replication Repair of

Modeling of the interaction between RAD52 DNA binding domain 1 and

Interaction with RPA Is Necessary for Rad52 Repair Center Formation and

Models of SmallMolecule Inhibition of RAD52 A Models of 6OHdopa

Distinct RAD51 Associations with RAD52 and BCCIP in Response to DNA

Transcriptomics and Proteomics Analysis of the Liver of RAD52 Knockout Mice

Structural Basis of HomologyDirected DNA Repair Mediated by RAD52

Human RAD52 stimulates the RAD51mediated homology search Life

Rad52 forms DNA repair and recombination centers during S phase PNAS

RAD52 locates to resected DSBs to prevent their repair in G2phase

RAD52dependent mitotic DNA synthesis is required for genome stability

Novel Insights into RAD52s Structure Function and Druggability for

Stressing Out About RAD52 Molecular Cell

Frontiers RAD52 Paradigm of Synthetic Lethality and New Developments

Scientists Discover New Way To Target HardToTreat Cancers

Novel Insights into RAD52s Structure Function and Druggability for

RAD52dependent mitotic DNA synthesis is required for genome stability

LOGO

RAD51 protects human cells from transcriptionreplication conflicts

6OHdopa Dissociates RAD52ssDNA Complexes and Acts as a Download

Novel Insights into RAD52s Structure Function and Druggability for

RAD52dependent mitotic DNA synthesis is required for genome stability

6OHdopa Dissociates RAD52ssDNA Complexes and Acts as a Download

Frontiers RAD52 Paradigm of Synthetic Lethality and New Developments

Location of mutated residues on the structure of RAD52 A The

Smallmolecule inhibitors identify the RAD52ssDNA interaction as

Doublestranded DNA binding function of RAD51 in DNA protection and its

Biophilia Donuts and Zippers for DNA Repair

Organization and functional consequences of the DNA damage response

IJMS Free FullText Dihydrocoumarin an HDAC Inhibitor Increases

Smallmolecule inhibitors identify the RAD52ssDNA interaction as

Targeting HR Repair as a Synthetic Lethal Approach to Increase DNA

BRCA1 and RNAi factors promote small RNA and PalB2Rad52 mediated

Smallmolecule inhibitors identify the RAD52ssDNA interaction as

IJMS Free FullText Dihydrocoumarin an HDAC Inhibitor Increases

RAD52s active form is not a ring PNAS

An Rloopinitiated CSBRAD52POLD3 pathway suppresses ROSinduced

Smallmolecule inhibitors identify the RAD52ssDNA interaction as

Novel Insights into RAD52s Structure Function and Druggability for

RPA:RAD52:MRE11 suppression reduces the toxicity of Polθ depletion a ...

RPARAD52MRE11 suppression reduces the toxicity of Pol depletion a

Targeting HR Repair as a Synthetic Lethal Approach to Increase DNA

IJMS Free FullText Dihydrocoumarin an HDAC Inhibitor Increases

Purification of rad52327 and mutants A functional domains in the S

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