Pgrn Color

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Subcellular localization of PGRN PGRN variants and TDP43

PGRN is mainly localized in neuron and activated macrophagemicroglia

PSAP and PGRN in PD patients are divergently regulated and associated

PGRN processing is lysosomedependent a Primary Sort Grn

Subcellular localization of PGRN PGRN variants and TDP43

PGRN is elevated in the peripheral blood and discs of patients with

The effects of PGRN on microglial autophagy A Representative TEM

PSAP is required for PGRN lysosomal targeting in fibroblasts A

Protein expression of PGRN in aortic tissue in different groups NC

PGRN is expressed in disc tissues of both human and mice and its level

Changes in PGRN mouse placentas and embryos A HE staining of a

A C Sequence chromatographs demonstrating PGRN mutations in FTLD

The protein sequence of full length PGRN and its proteolytically

Progranulin PGRN structure and its derivative products PGRN is

CD68 binds PGRN and granulin E via the mucinprolinerich domain A

Measurement of PGRN levels in the CSF by ELISA A Example of standard

Effect of PGRN on nuclear translocation of NF-κB p65. Cells treated ...

Effect of PGRN on nuclear translocation of NFB p65 Cells treated

The expression level of PGRN in lung cancer tissues and lung cancer

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PGRN treatment promotes cerebral ischemiainduced neural stem cells

Phylogenetic tree and synteny analysis of the PGRN family A

AAVmediated PGRN expression corrects lysosomal pathology in brains of

PGRN interactions trafficking and proteolysis Several PGRN receptors

Protein interactions network In the figure green color indicates

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PGRN expression within the dissociated spinal cordDRG cultures

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Immunohistochemical localization of PGRN in human temporal cortex

PGRN immunolabeling following ND602 A Representative Download

Changes of PGRN expression on periodontium tissue in compression side

The level of PGRN was significantly reduced in the kidney under

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Overexpression of PGRN in most GBM tumors a Western blot WB of

PGRN missensemutations are impaired in secretion A schematic

PGRN does not affect CD68 localization A WT and Grn BMDMs were

PGRN Levels in iPSCDerived Microglia Related to Figure 3 Download

PGRN content in LCLs from WT controls and heterozygous and homozygous

REST repress PGRN promoter activity a Putative REST binding

PGRN binds to Rab2 and Grn E is the major binding domain for A

In addition to NII all cases with PGRN mutations showed similar

Effects of PGRN on the differentiation of human OCs and PGRN as a

Measurement of PGRN levels in the CSF by ELISA A Example of standard

The influences of PGRN on proliferation in PTC cells A B Knockdown

Differences of PGRN and CDK4 protein expression between gastric cancer

PGRN interactions trafficking and proteolysis Several PGRN receptors

PGRN promotes cell cycle progression and cell proliferation in gastric

PGRN protein content and secretion in human TDP43 LOF cells a

Expression and distribution of PGRN in the NAc following NAc

Selective transduction of neurons with PGRN and LPGRN protects

Upregulation of Pgrn expression was correlated with poor prognosis and

The effect of PGRN on retinal precursor cells in primary culture A

PGRN interactions trafficking and proteolysis Several PGRN receptors

Serum PGRN levels and its correlation with clinical characteristics

Hypothesis Based on all available data we hypothesize that PGRN plays

PGRN missensemutations are impaired in secretion A schematic

PGRN is an endogenous antiHIV factor Microglial PGRN was knocked down

PGRN is induced during influenza virus infection A PGRN mRNA

Serum PGRN levels and its correlation with clinical characteristics

Schematic model of the proposed signal pathways of PGRN effect in

The protein sequence of full length PGRN and its proteolytically

PGRN

PGRN deficiency exacerbates whereas a brain penetrant PGRN derivative

Transduction with PGRN or LPGRN does not alter baseline neuronal

PGRN binds to HexA through granulins G and E a CoIP assay to test the

PGRN processing in PSAPdeficient mice A B Western blot analysis of

PGRN mutations identified in FTLD patients Schematic representation of

PGRN deficiency promoted neuroinflammation by ex vivo ELISA test

PGRN deficiency results in decreased GCase activity in mouse tissues

Histomorphometry of cancellous bone at distal femur in 6moold PGRN KO

PGRN does not affect CD68 localization A WT and Grn BMDMs were

Pgrn expression in the CNS of aged GrnR493XR493X mice 18 month old

PGRN within motor neurons in primary cultures does not colocalize with

ROC curves of serum and urine PGRN levels and the combination of the

Median level of PGRN is 1206 ngmL IQR 9781471 and PGRN level is

Measurement of PGRN levels in the CSF by ELISA A Example of standard

Surgical trauma and implant can increase plasma and local PGRN levels

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Schematic model of the proposed signal pathways of PGRN effect in

PGRN

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Wiktionary

Deficiency in progranulin PGRN does not affect vascular inflammatory

The Role of Progranulin PGRN in the Pathogenesis of Glioblastoma

Deficiency in progranulin PGRN does not affect vascular inflammatory

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Development of Pcgin a Overexpression of PGRN but not its mutant

The Role of Progranulin PGRN in the Pathogenesis of Glioblastoma

Progranulin PGRN is upregulated in neuroinflammation in vivo AC

Effect of PGRNGRN on soma size and neurite outgrowth AD NFH

Full article Progranulin as a Potential Therapeutic Target in Immune

Lysosomal functions of progranulin and implications for treatment of

Detection of progranulin PGRN protein in rheumatoid arthritis RA

Parkin Levels Decrease in Fibroblasts With Progranulin PGRN

Progranulin PGRN Marker of Neuroinflammation

AntiProgranulin Antibody AF2420 RD Systems

Level of progranulin PGRN was increased in wildtype WT mice after

Human ProgranulinPGRN Antibody AF2420 by RD Systems Part of BioTechne

科学网—Nature Communi——额颞叶痴呆PGRN突变导致prosaposin运输异常 - 陈之春的博文

Nature CommuniPGRNprosaposin

Enhanced progranulin PGRN expression in airway epithelial cells of a

Human ProgranulinPGRN Antibody R D SystemsAntibodiesPrimary

ProgranulinPGRN antibody 184101AP Proteintech

Some Features of PGRN microglia and Alzheimers disease A Confocal

Passage Bio Inc Our Science Role of Progranulin

Human ProgranulinPGRN Antibody AF2420 by RD Systems Part of BioTechne

Human ProgranulinPGRN Antibody AF2420 RD Systems

ProgranulinPGRN antibody 184101AP Proteintech

Summary of our findings Progranulin PGRN activates endothelial

ProgranulinPGRN antibody 861182RR Proteintech

Full article A new GRN variant in logopenic variant primary

The Role of Progranulin PGRN in the Pathogenesis of Glioblastoma

Human ProgranulinPGRN Antibody AF2420 by RD Systems Part of BioTechne

Mouse ProgranulinPGRN Antibody AF2557 RD Systems

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Human ProgranulinPGRN Antibody AF2420 RD Systems

Mouse ProgranulinPGRN Antibody AF2557 RD Systems

Progranulin protects against osteoarthritis through interacting with

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