Pml Sumo Inhibition

The SUMO E3ligase PIAS1 regulates the tumor suppressor PML and its

Inhibition of PML SUMOylation by IE1 A HEK293T cells were

Pharmacological inhibition of the SUMO pathway inhibits TGF-β1-induced ...

Pharmacological inhibition of the SUMO pathway inhibits TGF1induced

SUMO modification mutants of PML are defective in recruitment to sites

A role for SUMO in the formation of new PML bodies A Download

Solved SUMO modification SUMO binding Recruitment PML PML Cheggcom

PML NB nucleation does not depend on SUMO interactions with SIM A

Viruses can target the Sumo pathway to disrupt PMLNBs a Several

The SUMO Pathway in Hematomalignancies and Their Response to Therapies

Oxidative stressinduced assembly of PML nuclear bodies controls

PDF SUMO and the cellular stress response

The Dynamic Regulation of DaxxMediated Transcriptional Inhibition by

Reversible modification of proteins by SUMO and its Download

Figure 1 from Comparison of the SUMO 1 and ubiquitin conjugation

Exploration of nuclear bodyenhanced sumoylation reveals that PML

Increase in the SUMOylation of nuclear PML isoforms in response to As 2

Frontiers PML Degradation Multiple Ways to Eliminate PML

PML multimerizes and is deSUMOylated in response to different

Acetylation of SUMO1 Alters Interactions with the SIMs of PML and Daxx

Arsenic induces SUMO modification and proteasomedependant degradation

Twocolor 4Pi microscopy images of PML and SUMO Immunostaining was

PML acetylation is associated with enhanced sumoylation A p300

Manipulating PML SUMOylation via Silencing UBC9 and RNF4 Regulates

The Human Cytomegalovirus IE1 Protein Antagonizes PML Nuclear Body

Role of SUMO in RNF4mediated Promyelocytic Leukemia Protein PML

SUMOylation of PIAS1 promotes its PML localization a Distribution of

SUMO E3 ligase activity of TRIM proteins PMC

The SUMO Pathway in Hematomalignancies and Their Response to Therapies

Model of PML nuclear body NB assembly 1 PML NB biogenesis is

SUMOylation of PIAS1 promotes its PML localization a Distribution of

Targeting SUMO Signaling to Wrestle Cancer Trends in Cancer

Multiple SUMO substrates can be captured by SUBEl SUMOylated A

Frontiers SUMO and SUMOylation Pathway at the Forefront of Host

Manipulating PML SUMOylation via Silencing UBC9 and RNF4 Regulates

Accumulation of PML SUMO1 conjugation in the nucleus a K490 is the

The SUMO Pathway in Hematomalignancies and Their Response to Therapies

Targeting oncogenic PML in acute promyelocytic leukemia Both agents

Differential effects of the IE1 and SUMO proteases on the formation of

Full article PML nuclear bodies Assembly and oxidative stress

PML is required for stress response and sumoylation in mESCs and mice a

Targeting SUMO Signaling to Wrestle Cancer Trends in Cancer

IFNs increase PML SUMOylation in SUMO3expressing cells resulting in

The mechanisms of the SUMO pathway Step 1 maturation The small

Effect of interference with PML SUMOylation by GA or UBC9 knockdown on

Degradation of SUMOylated JARID1B and PML Is Mediated by the

Z sumodefective mutants are partially inhibited for PML body

The Dynamic Regulation of DaxxMediated Transcriptional Inhibition by

Sumoylation of PML modulates Daxxmediated transcriptional

Twocolor 4Pi microscopy images of PML and SUMO Immunostaining was

The Dynamic Regulation of DaxxMediated Transcriptional Inhibition by

PML promotes Sp1 SUMOylation in vivo and in vitro A The consensus

Therapeutic Potential of Targeting the SUMO Pathway in Cancer

PDF The SUMO pathway Emerging mechanisms that shape specificity

Manipulating PML SUMOylation via Silencing UBC9 and RNF4 Regulates

Domains involved in the interaction of PML with SUMO1 and UBC9 A

Targeting SUMO Signaling to Wrestle Cancer Trends in Cancer

Detection by BRET of the increase in the SUMOylation of nuclear PML

SUMO1 modification and subcellular localisation of PML 97 kDa and

Role of SUMO in RNF4mediated Promyelocytic Leukemia Protein PML

PML NB partners and NBtriggered biological responses a PML

Effects of ATO and Ang II on PML SUMOylation and PMLNBs formation

SUMO E3 ligases in the regulation of the hallmarks of cancer SUMO E3s

PML IVARF interaction enhances p53 SUMO1 conjugation activation and

SUMO binding is required for paralogselective sumoylation of BLM in

Effects of ATO and Ang II on PML SUMOylation and PMLNBs formation

Role of SUMO in RNF4mediated Promyelocytic Leukemia Protein PML

Acetylation of SUMO1 Alters Interactions with the SIMs of PML and Daxx

The Dynamic Regulation of DaxxMediated Transcriptional Inhibition by

SUMOylation Promotes PML Degradation during Encephalomyocarditis Virus

PDF Exploration of nuclear bodyenhanced sumoylation reveals that PML

Role of SUMO in RNF4mediated Promyelocytic Leukemia Protein PML

SUMO5 conjugates PML as polymeric chains A SUMO5 can conjugate PML

The SUMO enzymatic pathway SUMO paralogs are synthesized as inactive

Acetylation of SUMO1 Alters Interactions with the SIMs of PML and Daxx

PML IVARF interaction enhances p53 SUMO1 conjugation activation and

Modification of nuclear PML protein by SUMO1 regulates Fasinduced

The formation of APBs is independent of the SUMOylation of the PML

Representation of the SUMOylation pathway in relation to the PMLNB

Frontiers SUMO Glue or Solvent for PhaseSeparated Ribonucleoprotein

Frontiers A Tale of Usurpation and Subversion SUMODependent

Frontiers PML SUMOylation and Senescence

ATOdependent PMLRARA SUMOylation and degradation ATO triggers

Structural and Functional Characterization of the Phosphorylation

Frontiers PML SUMOylation and Senescence

Diagnostic and Therapeutic Implications of the SUMOylation Pathway in

A new immunooncology target SUMOylation Trends in Cancer

The Mechanisms of PMLNuclear Body Formation Molecular Cell

ATOdependent PMLRARA SUMOylation and degradation ATO triggers

Novel insights into the impact of the SUMOylation pathway in

Figure 1 from SmallMolecule Inhibitors Targeting Protein SUMOylation

Immunoprecipitation with antiSUMO1 and antiSUMO23 antibodies THP1

Structural and Functional Characterization of the Phosphorylation

SUMO The Glue that Binds Developmental Cell

Crosstalk between SUMOylation and PMLinduced cellular senescence An

Structural characterization of a SUMO1PMLSIM4SDZn complex A

Reprogramming SUMOprimed ubiquitylation opportunities in oncology and

Inhibiting ubiquitination causes an accumulation of SUMOylated newly

SUMO5 facilities the formation of PMLNBs A The conjugation site and

Promyelocytic Leukemia Protein PML Regulates Stem Cell Pluripotency

Structural and Functional Characterization of the Phosphorylation

Targeting SUMOylation in ovarian cancer Sensitivity resistance and

A Tale of Usurpation and Subversion SUMODependent Integrity of

Effects of Vpu on SUMOylation and PMLNBs a PLA for BLMSUMO

Nuclear Organization and PostTranslational Control in PhysioPathology

Sumoylation and human disease pathogenesis Trends in Biochemical Sciences

How ubiquitin and SUMOs control trx MBV

SUMOmodified PML but not RanGAP1 is efficiently deconjugated by

Promyelocytic Leukemia Protein PML Regulates Stem Cell Pluripotency

A Proteomic Study of SUMO2 Target Proteins Journal of Biological

Structural characterization of a SUMO1PMLSIMZn complex A Overall

Promyelocytic Leukemia Protein PML Requirement for Interferoninduced

Compositional Control of PhaseSeparated Cellular Bodies Cell

TRIB3 Promotes APL Progression through Stabilization of the Oncoprotein

Colocalization of ErbB4 with SUMO1 PIAS3 and PML A COS7 cells

Novel insights into the impact of the SUMOylation pathway in

PML SUMO and RNF4 Guardians of Nuclear Protein Quality Molecular Cell

SUMO From Bench to Bedside Physiological Reviews American

Novel insights into the impact of the SUMOylation pathway in

SUMO5 facilities the formation of PMLNBs A The conjugation site and

Competition for SUMO5 conjugation from PMLRAR causes cytoplasmic

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