Pld2 Cancer

A new model highlighting the regulation of PLD2 by phosphorylation

In This Issue 2025 Cancer Science Wiley Online Library

Biphasic regulation of PLD2 activity by tyrosine phosphatases in vitro

Proposed model for the interactions of PARN with PLD2 in noncancerous

Functional Regulation of Phospholipase D Expression in Cancer and

Two sites of action for PLD2 inhibitors The enzyme catalytic center

Dynamics of differential regulation of PLD expression in cancer

PLD2 regulation of the nuclear ERK activity is a common mechanism of

PLD2 as a GEF We modeled PLD2 structural domains and found that its PH

PLD2 interacts with cFms and PI3K a Endogenous PLD2 in BMMs was

Cell Invasion of highly metastatic MTLn3 cancer cells is dependent on

Immunolocalization of PLD2 by using an antibody generated to a

The relationship of tumor size and expression of PLD2 in human

Motifs and domains found within mammalian PLDs including PLD1 PLD2 and

A new model highlighting the regulation of PLD2 by phosphorylation

PLD2 and Rac2 transmodulate each other A GEF activity of PLD2WT

PLD2 inhibition induces autophagy via Atg5 Atg7 and Ulk1mediated

PLD2 inhibition increases the onrate of autophagy a HT29 cells were

Bleb Formation in Human Fibrosarcoma HT1080 Cancer Cell Line Is

Increased PLD2 expression in CRC leads to elevated mortality and tumor

Bleb Formation in Human Fibrosarcoma HT1080 Cancer Cell Line Is

PLD2 has both a lipase and a GEF activity Both PX and PH protein

A new model highlighting the regulation of PLD2 by phosphorylation

Dynamics of differential regulation of PLD expression in cancer

PLD2 interacts with cFms and PI3K a Endogenous PLD2 in BMMs was

The PLD2PH domain suppresses the migration and invasion of cancer

Phospholipase D expression in lung cancer cells with alkylating agent

Localisation of PLD1 and PLD2 isoforms in RBLmast cells following

PKC phosphorylates PLD2 during integrinmediated cell spreading A

Table 1 from Phospholipase D in cell proliferation and cancer

Alternative phospholipase DmTOR survival signal in human breast cancer

PLD2 phospholipase D2

PDF Bleb Formation in Human Fibrosarcoma HT1080 Cancer Cell Line Is

Proposed model for the interactions of PARN with PLD2 in noncancerous

A PLD2 protein expression and B PLD lipase activity in

Bleb Formation in Human Fibrosarcoma HT1080 Cancer Cell Line Is

PLD2 activation and cell spreading require the PKC mediated

Cancer Science Vol 116 No 2

PLD2 activation and cell spreading require the PKC mediated

PLD2 lies upstream of myosin II in the cellspreading signaling

Figure 2 from PLD2 Complexes with the EGF Receptor and Undergoes

Domain structure of PLD1 and PLD2 from mammals yeast plant bacteria

Activation of PLD2 by PtdIns45P 2 does not require the Download

LpPLA2 in the cancer landscape From molecular mechanisms to

PLD2 lies upstream of myosin II in the cellspreading signaling

The Exquisite Regulation of PLD2 by a Wealth of Interacting Proteins

Bleb Formation in Human Fibrosarcoma HT1080 Cancer Cell Line Is

The exquisite regulation of PLD2 by a wealth of interacting proteins

Figure 1 from Decreased Expression of PLD2 Promotes EMT in Colorectal

Dysregulation of phospholipase D1 PLD1 and PLD2 activity in human

Frontiers Programmed cell deathligand 2 new insights in cancer

PLD2 is located in the cell membrane of advancing pseudopodia in early

The exquisite regulation of PLD2 by a wealth of interacting proteins

Increased PLD2 expression in CRC leads to elevated mortality and tumor

Immunolocalization of PLD2 by using an antibody generated to a

Overexpression of either PLD1 or PLD2 provides a survival signal in 3Y1

Phospholipase D in Cell Signaling From a Myriad of Cell Functions to

PDF Phosphatidic acid phospholipase D and tumorigenesis

Phospholipase D2 promotes disease progression of renal cell carcinoma

Binding of PLD2Generated Phosphatidic Acid to KIF5B Promotes MT1MMP

A New Signaling Pathway JAKFesphospholipase D That Is Enhanced in

THE MECHANISM OF CELL MEMBRANE RUFFLING RELIES ON A PHOSPHOLIPASE D2

Phospholipase D PLD drives cell invasion tumor growth and metastasis

Design of isoformselective phospholipase D inhibitors that modulate

Phospholipase D2 in prostate cancer protein expression changes with

Model of PLD2PAregulated PTPN14 in VEcadherin stabilization at

Phospholipase D2 downregulates interleukin‐1β secretion from tumor ...

Phospholipase D2 downregulates interleukin1 secretion from tumor

A New Signaling Pathway JAKFesphospholipase D That Is Enhanced in

Phospholipase D Is Involved in the Formation of Golgi Associated

Physiological function of phospholipase D2 in antitumor immunity

Phospholipase D2 a distinct phospholipase D isoform with novel

Phospholipase D2 Localizes to the Plasma Membrane and Regulates

Phospholipase D PLD inhibitors in combination with radiation augment

Phospholipase D2 Localizes to the Plasma Membrane and Regulates

Phospholipase D PLD drives cell invasion tumor growth and metastasis

Phospholipase D2 Localizes to the Plasma Membrane and Regulates

Oncology Letters

Phospholipase D2 Localizes to the Plasma Membrane and Regulates

Oncology Letters

Effects of Active and Inactive Phospholipase D2 on Signal Transduction

Phospholipase D2 promotes disease progression of renal cell carcinoma

Phospholipase D PLD drives cell invasion tumor growth and metastasis

Phospholipase D2 controls bone homeostasis by modulating MCSF

Phospholipase D2 a distinct phospholipase D isoform with novel

The Direct Interaction of Phospholipase C-γ1 with Phospholipase D2 Is ...

The Direct Interaction of Phospholipase C1 with Phospholipase D2 Is

Phospholipase D PLD inhibitors in combination with radiation augment

Binding of PLD2Generated Phosphatidic Acid to KIF5B Promotes MT1MMP

Identification of the Catalytic Site of Phospholipase D2 PLD2 Newly

Oncology Letters

Phospholipase D2 promotes degradation of hypoxiainducible factor1

International Journal of Oncology

Interaction of the Type Iα PIPkinase with phospholipase D: a role for ...

Interaction of the Type I PIPkinase with phospholipase D a role for

Computer generated prediction of matchup between LARG and SWAP70 with

LIPIDS Illustrating human PLD PMC

Physiological function of phospholipase D2 in antitumor immunity

Effects of Active and Inactive Phospholipase D2 on Signal Transduction

Identification of the Catalytic Site of Phospholipase D2 PLD2 Newly

Phospholipase D2 PLD2 is a guanine nucleotide exchange factor GEF

Oncology Letters

Phospholipase D2 PLD2 Shortens the Time Required for Myeloid Leukemic

Inhibition of PLD The figure shows the schematic structure of

THE MECHANISM OF CELL MEMBRANE RUFFLING RELIES ON A PHOSPHOLIPASE D2

Molecular Analysis of Mammalian Phospholipase D2 Journal of

The Role of Phospholipase D in Modulating the MTOR Signaling Pathway in

Binding of PLD2Generated Phosphatidic Acid to KIF5B Promotes MT1MMP

Phospholipase D2 PLD2 Shortens the Time Required for Myeloid Leukemic

Binding of PLD2Generated Phosphatidic Acid to KIF5B Promotes MT1MMP

Proposed model for a high PLD expression in TNBC cells due to a low

Binding of PLD2Generated Phosphatidic Acid to KIF5B Promotes MT1MMP

Exosome Secretion and EpithelialMesenchymal Transition in Ovarian

Effects of Active and Inactive Phospholipase D2 on Signal Transduction

OXIDIZED LDL PHAGOCYTOSIS DURING FOAM CELL FORMATION IN ATHEROSCLEROTIC

Phospholipase D2 a distinct phospholipase D isoform with novel

Frontiers Aldolase A and Phospholipase D1 Synergistically Resist

Hypothetical scheme of PLD PLD1 and PLD2 involvement in human

Effect of 15C in the distribution of PLD1 and PLD2 Cells were

Effects of Active and Inactive Phospholipase D2 on Signal Transduction

Phospholipase D2 PLD2 Shortens the Time Required for Myeloid Leukemic

Phospholipase D PLD drives cell invasion tumor growth and metastasis

Pd1 And Pd L1 In Cancer

Pd L1 Expression In Cancer

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