Pcna Rad18

Rad18 dependent monoubiquitination of PCNA by Rad18 and Rad6AB in vivo

The Rad18 RING finger is not involved in stimulating PCNA SUMOylation

Polη physically bridges Rad18 and PCNA to promote efficient PCNA ...

Pol physically bridges Rad18 and PCNA to promote efficient PCNA

Physical bridging of Rad18 and PCNA by PolZ is dissociable from its DNA

Figure 1 from SIVA1 directs the E3 ubiquitin ligase RAD18 for PCNA

PDF SIVA1 directs the E3 ubiquitin ligase RAD18 for PCNA

Polη promotes damage-induced Rad18 redistribution and PCNA ...

Pol promotes damageinduced Rad18 redistribution and PCNA

RAD18 or UBC13 knockdown disrupts PCNA polyubiquitination A Hela

SUMO as a regulator of PCNA ubiquitylation and repair pathway choice

E3 ligase Rad18 promotes monoubiquitination rather than ubiquitin chain

Cell Type Specific Suppression of HyperRecombination by Human RAD18 Is

RAD18 Is a Maternal Limiting Factor Silencing the UVDependent DNA

Regulation of PCNA monoubiquitination in human cells Blockage of the

Dynamic regulation of PCNA ubiquitylationdeubiquitylation Fox 2011

Rad18 interaction with its target PCNA S200 analytical gel filtration

Interaction of Human DNA Polymerase η with Monoubiquitinated PCNA ...

Interaction of Human DNA Polymerase with Monoubiquitinated PCNA

The L154 residue of PCNA is involved in interaction with Rad18 a The

In vitro reconstitution of PCNA polyubiquitylation A Modification

Human Rad18 is unaffected by fusion of SUMO to PCNA In vitro

Contributions of p53 and Chk1 signalling to Polη-facilitated PCNA ...

Contributions of p53 and Chk1 signalling to Polfacilitated PCNA

Restoration of CPT sensitivity and UVinduced PCNA monoubiquitination

RAD18 participates in cisplatininduced FANCD2 monoubiquitylation

Interactions and activities of Rad18 towards sumoylated PCNA A

Two step Rev1Polzdependent TLS After PCNA monoubiquitination by

PCNA ubiquitylation influences PCNA chromatin association A PCNA

RAD18 participates in two distinct DNA repair pathways a RAD18 is

Interactions and activities of Rad18 towards sumoylated PCNA A

Rad18 S409 is dispensable for Rad18Rad6 interactions PCNAdirected E3

ATR limits Rad18mediated PCNA monoubiquitination to preserve

Interactions and activities of Rad18 towards sumoylated PCNA A

Rad18mediated monoubiquitination of PCNA is required for its

PDF Functional characterization of Rad18 domains for Rad6 ubiquitin

A Colocalization of labeled DNAPt with RAD18 in U2OS cells Cells

Figure 1 from RAD18mediated ubiquitination of PCNA activates the

Ubiquitinated PCNA mediates TLS and TS When the replication fork

Schematic representation of ligandinteracting regions of human Rad18

Rad18mediated monoubiquitylation of PCNA is required for its

DNA damageinduced association between GFPPol and PCNA requires

The L154 residue of PCNA is involved in interaction with Rad18 a The

Rad18 E3 ubiquitin ligase activity mediates Fanconi anemia pathway

Impacts of Arsenic on Rad18 and Translesion Synthesis PMC

Ubiquitinated PCNA mediates TLS and TS When the replication fork

PDF RAD18mediated ubiquitination of PCNA activates the Fanconi

6 RAD18 known substrates RAD18 ubiquitinates a limited number of known

Rad18Rad5Mms2mediated polyubiquitination of PCNA is implicated in

Overview of DNA damage tolerance pathways and PCNA ubiquitination

Rad18 guides polη to replication stalling sites through physical ...

Rad18 guides pol to replication stalling sites through physical

Alternative models for the mechanism of PCNA polyubiquitylation by

Influence of Rad6Rad18 and DNARFC on PCNA polyubiquitylation A

7 RAD18 role in interstrand crosslink ICL repair pathway Haynes et

A The genetics of PCNA monoubiquitination PCNA is monoubiquitinated

Rad6/Rad18 Competes with DNA Polymerases η and δ for PCNA Encircling ...

Rad6Rad18 Competes with DNA Polymerases and for PCNA Encircling

RAD18 but not Cdt2 mediates PCNA monoubiquitylation to promote

PCNA ubiquitylation influences PCNA chromatin association A PCNA

PCNA monoubiquitination stimulates on the fly TLS a Western blot of

Rad18mediated ubiquitination and Siz1mediated sumoylation of PCNA are

RAD18 accumulates at sites of DNA damage induced by UVA laser

Cell Type Specific Suppression of HyperRecombination by Human RAD18 Is

MAGEA4 promotes RAD18 stability a Recombinant RAD18RAD6 complex

Cell Type Specific Suppression of HyperRecombination by Human RAD18 Is

Oncogenic stimuli promote RAD18mediated PCNA monoubiquitination A

PDF Rad18Rad5Mms2mediated polyubiquitination of PCNA is implicated

Reaction mechanisms of PCNA polyubiquitinationA Chainformation

Polyubiquitination of PCNA by en bloc Ub chain transfer A In vitro

Relevance of the SIMSUMO interaction for Rad18 function in vivo A

Rad18 guides pol to replication stalling sites through physical

Influence of Rad6Rad18 and DNARFC on PCNA polyubiquitylation A

Physical interaction between Rad18 and Polη drives efficient ...

Physical interaction between Rad18 and Pol drives efficient

Oncogenic stimuli promote RAD18mediated PCNA monoubiquitination A

REV1 promotes the recruitment of RAD18 to chromatin A 293T cells

Full article Rad18 E3 ubiquitin ligase activity mediates Fanconi

SHPRH physically interacts with PCNA UBC13 and RAD18 and

SART3 depletion impairs UVinduced PCNAmUb and RAD18 focus formation

ATR limits Rad18mediated PCNA monoubiquitination to preserve

The inner side of yeast PCNA contributes to genome stability by

Oncogenic stimuli promote RAD18mediated PCNA monoubiquitination A

Cell Type Specific Suppression of HyperRecombination by Human RAD18 Is

Rad18 guides pol to replication stalling sites through physical

Hypothetical model for functional redundancy of Rad18 and NHEJ in

NBS1 Recruits RAD18 via a RAD6like Domain and Regulates Pol

ATR limits Rad18mediated PCNA monoubiquitination to preserve

Rad18 guides pol to replication stalling sites through physical

A revised working model of DNAdamage tolerance in budding yeast Under

Roles of Rad6Rad18mediated ubiquitin conjugation and Ubc9mediated

The function of NBS1 in translesion DNA synthesis NBS1 interacts with

Activation of UbiquitinDependent DNA Damage Bypass Is Mediated by

Rad18mediated Translesion Synthesis of Bulky DNA Adducts Is Coupled to

PDF A series of xanthenes inhibiting Rad6 function and Rad6Rad18

Replication protein A dynamically regulates monoubiquitination of

Noncanonical Mismatch Repair as a Source of Genomic Instability in

Rad18mediated Translesion Synthesis of Bulky DNA Adducts Is Coupled to

DNA Damage Bypass

Breakinduced telomere synthesis promotes RAD18dependent interaction

Role of the Rad6 epistasis group in DNA damage bypass The ringshaped

Rad6Rad18 complex expression and E3ligase activity A Residue

Monoubiquitination of Proliferating Cell Nuclear Antigen Induced by

A model for the role of Rad6Rad18dependent monoubiquitination Ub

The RAD18ubiquitinated PCNASNM1A axis mediates template Download

Parkin regulates translesion DNA synthesis in response to UV radiation

Rad6Rad18 Mediates a Eukaryotic SOS Response by Ubiquitinating the 91

Full article Building up and breaking down mechanisms controlling

Rad6Rad18 Mediates a Eukaryotic SOS Response by Ubiquitinating the 91

A series of xanthenes inhibiting Rad6 function and Rad6Rad18

5 RAD18 Pol and REV1 localize to sites of cisplatininduced

Rad6Rad18 complex expression and E3ligase activity A Residue

A series of xanthenes inhibiting Rad6 function and Rad6Rad18

In and out of Replication Stress PCNARPA1Based Dynamics of Fork

Figure 1 from A SUMOinteracting motif activates budding yeast

NEDDylation antagonizes ubiquitination of proliferating cell nuclear

Identification of a SUMOinteracting motif in Rad18 A Domain

ING1b is required for Rad18mediated PCNAUb during stalled

Evidence for a Rad18Independent Frameshift Mutagenesis Pathway in

Monoubiquitination of PCNA A UV light or HUinduced Download

MicroRNA3795p attenuates cancer stem cells and reduces cisplatin

Monoubiquitination of PCNA A UV light or HUinduced Download

陈玮团队《Nat Immunol》揭示E3泛素连接酶RAD18可终止IRF3驱动的IFNB1转录-中国免疫学会

Nat ImmunolE3RAD18IRF3IFNB1

Schematic view of the roles of SPCNA and Srs2 in the rescue of stalled

A series of xanthenes inhibiting Rad6 function and Rad6Rad18

Two replication fork maintenance pathways fuse inverted repeats to

Pcna DNA

Pcna Ubiquitination

Translesion DNA Synthesis

Rad 140 Transformation

RAD18 Blot 56Kd

PCNA Polyδ

Monoclonal Antibody Product

Polδ PCNA Fen1lihuilin

Electroporation Lonza

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