Inpp5e Rab8a

Frontiers INPP5E and Coordination of Signaling Networks in Cilia

INPP5E and phosphoinositides A INPP5E domain structure An inositide

Frontiers DownRegulation of Inpp5e Associated With Abnormal

Deletion of the phosphatase INPP5E in the murine retina impairs

INPP5E structure and protein variants a INPP5E secondary structure

ARL13B PDE6D and CEP164 form a functional network for INPP5E ciliary

INPP5E regulates the spindle assembly checkpoint A Assay schematic

Proposed model for the role INPP5E plays at cilia PI45P2 pink

Loss of INPP5E causes genomic instability A and B Chromosome

Retinaspecific KO of INPP5E A INPP5E major functional domains

Figure 7 from A transient role of the ciliary gene Inpp5e in

INPP5E regulates Hedgehog signalling via ciliary phosphoinositide

Scrutiny of individual variants example for INPP5E variants A

Deletion of the phosphatase INPP5E in the murine retina impairs

The autophagy protein ATG16L1 cooperates with IFT20 and INPP5E to

INPP5E accumulates at the immune synapse in activated T cells a Jurkat

Deletion of the phosphatase INPP5E in the murine retina impairs

Rab8a as a mitochondrial receptor for lipid droplets in skeletal muscle

Phosphatase activity and lysosomal localization of INPP5E are needed

Ciliary axonemal localization of INPP5E and enhanced ciliary lability

INPP5E Preserves Genomic Stability through Regulation of Mitosis PMC

Rab8a as a mitochondrial receptor for lipid droplets in skeletal muscle

INPP5E protein expression is cell cycle dependent A and B Serum

Proposed model for the role Inpp5e in ciliogenesis through

Full article INPP5E Preserves Genomic Stability through Regulation of

Rab8a as a mitochondrial receptor for lipid droplets in skeletal muscle

Nuclear localization of INPP5E in interphase and mitosis A and B

Rab8a as a mitochondrial receptor for lipid droplets in skeletal muscle

The ciliary phosphatidylinositol phosphatase Inpp5e plays positive and

Rab35 depletion disrupts the ciliary levels of INPP5E and PIP45P 2

INPP5E modulates PI45P2 environment at the immune synapse a

The critical roles of INPP5E in maintaining the PIs on cilia membrane

INPP5E and OCRL domain structure and disease causing mutations INPP5E

Deletion of the phosphatase INPP5E in the murine retina impairs

Rab3GAPL interacts with Rab8a and stimulates its GTP hydrolysis

Phosphatidylinositol phosphate kinase PIPKIγ and phosphatase INPP5E ...

Phosphatidylinositol phosphate kinase PIPKI and phosphatase INPP5E

PDE6δ-mediated sorting of INPP5E into the cilium is determined by cargo ...

PDE6mediated sorting of INPP5E into the cilium is determined by cargo

Rab8a as a mitochondrial receptor for lipid droplets in skeletal muscle

Deletion of the phosphatase INPP5E in the murine retina impairs

Full article Role of Ocrl1 and Inpp5E in primary cilia assembly and

INPP5E accumulates at the immune synapse in activated T cells a Jurkat

ARL13B PDE6D and CEP164 form a functional network for INPP5E ciliary

PDE6D truncation leads to INPP5E ciliary mislocalization in patient

Figure 2 from A transient role of the ciliary gene Inpp5e in

RAB8A targeted to miR613 in CC cells A The predicted RAB8A binding

Role of Ocrl1 and Inpp5E in primary cilia assembly and maintenance a RRB

Ciliary axonemal localization of INPP5E and enhanced ciliary lability

Ciliary localization of INPP5E correlates with its binding to ARL13B

Germline deletion of Inpp5e leads to developmental abnormalities

Figure 9 from A transient role of the ciliary gene Inpp5e in

Deletion of the phosphatase INPP5E in the murine retina impairs

Full article INPP5E Preserves Genomic Stability through Regulation of

ARL13B PDE6D and CEP164 form a functional network for INPP5E ciliary

Rab8a is required for primary cilium formation A and B hTERTRPE1

Ectopic expression of INPP5E rescues olfactory cilia length in Bbs4 KO

The ciliary phosphatidylinositol phosphatase Inpp5e plays positive and

INPP5E Regulates the Distribution of Phospholipids on Cilia in RPE1

Figure 5 from A transient role of the ciliary gene Inpp5e in

INPP5E exhibits a ringshaped localization at the transition zone

Full article INPP5E Preserves Genomic Stability through Regulation of

Scrutiny of individual variants example for INPP5E variants A

Deletion of the phosphatase INPP5E in the murine retina impairs

Full article INPP5E Preserves Genomic Stability through Regulation of

Guanine nucleotide exchange factors activate Rab8a for Tolllike

A model for reciprocal interactions between INPP5E and AURKA A At

INPP5E and OCRL domain structure and disease causing mutations INPP5E

A transient role of the ciliary gene Inpp5e in controlling direct

Frontiers DownRegulation of Inpp5e Associated With Abnormal

Frontiers INPP5E and Coordination of Signaling Networks in Cilia

INPP5E ciliary targeting and binding to PDE6D are dependent upon

DownRegulation of Inpp5e Associated With Abnormal Ciliogenesis During

INPP5E Preserves Genomic Stability through Regulation of Mitosis PMC

Guanine nucleotide exchange factors activate Rab8a for Tolllike

The prolinerich domain is required for efficient INPP5E recruitment at

A transient role of the ciliary gene Inpp5e in controlling direct

Lack of INPP5E and PtdIns4P and accumulation of PtdIns45P 2 and

Interactions between AURKA and INPP5E affect the activity of both

PDE6mediated sorting of INPP5E into the cilium is determined by cargo

Phenotypic cellular and functional defects of inpp5e morphants can be

A model for reciprocal interactions between INPP5E and AURKA A At

Deletion of the phosphatase INPP5E in the murine retina impairs

A transient role of the ciliary gene Inpp5e in controlling direct

Protein quality control machinery supports primary ciliogenesis by

Volume 21 Issue 2

Functions of gene causing brain abnormality clarified ResOU

Modulation of Ciliary Phosphoinositide Content Regulates Trafficking

Induction of an Alternative mRNA 5 Leader Enhances Translation of the

The power of five inositol polyphosphate 5phosphatase gene mutations

Phosphoinositides Regulate Ciliary Protein Trafficking to Modulate

Protein quality control machinery supports primary ciliogenesis by

Domain organization of phosphatidylinositol 5 phosphatases inpp5B

磷脂酰肌醇磷酸激酶PIPKIγ和磷酸酶INPP5E协调纤毛发生的启动。,Nature Communications - X-MOL

PIPKIINPP5ENature Communications XMOL

Phosphoinositides Regulate Ciliary Protein Trafficking to Modulate

Ciliary axonemal localization of INPP5Ea RPEhTERT ciliated cells

Clinical phenotypes of INPP5EIRD patients Images show fundus photos

Phosphoinositides Regulate Ciliary Protein Trafficking to Modulate

Rab8 and TNPO1 are ciliary transport adaptors for GTPase Arl13b by

Induction of an Alternative mRNA 5 Leader Enhances Translation of the

Phosphoinositides metabolism and distribution Notes A The schematic

Full article Regulation of lysosomal phosphoinositide balance by

Modulation of Ciliary Phosphoinositide Content Regulates Trafficking

Induction of an Alternative mRNA 5 Leader Enhances Translation of the

Protein quality control machinery supports primary ciliogenesis by

IN1 treatment depletes pericentriolar Rab8apositive endosomes A

Autophagosome biogenesis and human health PMC

Protein quality control machinery supports primary ciliogenesis by

RPGR interacts with INPP5E A hTERTRPE1 cells transfected with

Molecular Medicine Reports

Schematic representation of the underlying mechanisms of olfactory

A subset of RabGAPs can block primary cilium formation A hTERTRPE1

Development of a Genetically Encoded and Potent PDE6D Inhibitor - Gómez ...

Development of a Genetically Encoded and Potent PDE6D Inhibitor Gmez

A Phosphoinositide Code for Primary Cilia Developmental Cell

Dynamic Remodeling of Membrane Composition Drives Cell Cycle through

AURKA levels are regulated by INPP5E A Immunofluorescence detection

Role of reverse phenotyping in interpretation of next generation

Virally induced ectopic expression of fulllength wild type human

Cells deleted for Pde6d display no defects in ciliation but loss of

Inpp5e Knockout Arl13b

Inpp5e in Photoreceptor

Inpp5e Ciliary Length

Cilia and Inpp5e and Arl13b

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