Isc Lgr5

Erdr1 induces ISC signature gene expression and Lgr5 ISCs a

IL22 reduces Lgr5 D ISC numbers and expression of active ISC markers in

Chromatin remodeling during dedifferentiation The Lgr5 ISC loss is

Apical constriction required for ISC function A Immunostaining of

Lgr5 Stem Cells Are Indispensable For Radiation Induced Intestinal

BCN057 rescued Lgr5 ISC and induced a regenerative response in vivo a

Lgr5 gene expression in normal human intestine a Schematic

Comparison of ISC marker expression in gastric adenomas with different

MDPNOD2 limit LGR5 ISCROS production GFPLGR5 organoids grown

NOTCH regulates BMI1LGR5 ISC division a LGR5EGFP mice were

An HFD increases ISC count in the colon Colon crypts were isolated

125Dihydroxyvitamin D Enhances the Regenerative Function of Lgr5

Redefining intestinal stemness The emergence of a new ISC population Cell

Intestinal niche microenvironment for ISC survival Tissueresident

The surface marker combination identifies the ISC population with CFE

NOTCH promotes asymmetric BMI1LGR5 ISC division a LGR5EGFP ISC

MDPNOD2 limit LGR5 ISCROS production GFPLGR5 organoids grown

Stem Cells Marked by the RSpondin Receptor LGR5 Gastroenterology

Larginine supplementation has no direct effect on Lgr5 ISC

A LGR5 reporter pig model closely resembles human intestine for

Znhit1 controls the transcription of Lgr5 ISC fatedetermining genes

Schematic representation of intestinal organoid growth from a Lgr5 ISC

CDX2 Is Required for Lgr5 ISC Proliferation and Differentiation

The intestinal stem cell markers Bmi1 and Lgr5 identify two

Schematic representation of intestinal organoid growth from a Lgr5 ISC

Shortterm lineage tracing of ISCs in Irf2 mice and ISC reduction

Reverse mRNA trajectories for ISC restoration A Cells isolated from

Model for ISC selfrenewal and differentiation a Under physiological

The intestinal stem cell markers Bmi1 and Lgr5 identify two

Chromatin remodeling during dedifferentiation The Lgr5 ISC loss is

Ccn1 deficiency leads to the ISC expansion and increased secretory

Schematic representation of intestinal organoid growth from a Lgr5 ISC

Intrinsic Autophagy Deficiency in ISCs Causes ISC Reduction A

Schematic representation of intestinal organoid growth from a Lgr5 ISC

NOTCH regulates the balance between LGR5 and BMI1 ISC populations

A regulatory loop between CCN1 and YAP during ISC homeostasis a

Muscarinic receptor blockade reduces Lgr5positive ISC tracing and

Lgr5 Egfp Ires Creert2 The Jackson Laboratory Bioz

Muscarinic receptor blockade reduces Lgr5positive ISC tracing and

Model for ISC selfrenewal and differentiation a Under physiological

MSC administration resulted in an increase in Lgr5 ISC progeny MSC

The LGR5 stem cell compartment is heterogeneous comprising a

Evidence that Lgr5 ISCs Transition into the IBP Population A

LGR5 staining in crypts of a healthy subject and subjects with CRC

HS diet reduces expression of proliferationrelated genes in Lgr5 D

Increased ISC regeneration and IL22 secretion in mice treated with

A LGR5 reporter pig model closely resembles human intestine for

LGR5 from stem cell marker to therapeutic target Trends in Cancer

Mex3a Marks a Slowly Dividing Subpopulation of Lgr5 Intestinal Stem

Lgr5 Stem Cells Are Indispensable for RadiationInduced Intestinal

A constant pool of Lgr5 intestinal stem cells is required for

Characteristics of Lgr5GFP ISCs in circPan3 mice a Representative

Modeling Intestinal Stem Cell Function with Organoids

Timeresolved fate mapping identifies the intestinal upper crypt zone

A constant pool of Lgr5 intestinal stem cells is required for

PDF Plasticity of Intestinal Epithelium Stem Cell Niches and

Notoginsenoside R1 promotes Lgr5 stem cell and epithelium renovation

A constant pool of Lgr5 intestinal stem cells is required for

Inhibiting NHE1 activity reduced Lgr5 ISCs a UMAP plot highlighting

CD90 stromal cells support Largininemediated Lgr5 ISC Download

Intestinal stem cell ISC single cell aging gene expression signature

Recent Advances in Lgr5 Stem Cell Research Trends in Cell Biology

Identification of Quiescent LGR5 Stem Cells in the Human Colon

膜与皮质的附着决定了 LGR5+ 和 LGR5- 结直肠癌细胞的不同机械表型,Nature Communications - X-MOL

LGR5 LGR5 Nature Communications XMOL

Identification of Quiescent LGR5 Stem Cells in the Human Colon

LGR5

Identification of Quiescent LGR5 Stem Cells in the Human Colon

Petosemtamab a Bispecific Antibody Targeting Epidermal Growth Factor

Lgr5 Stem Cells Are Indispensable for RadiationInduced Intestinal

Stem Cell Signaling Pathways in the Small Intestine

Recent Study Published in Nature Unravels a Novel Pathway for Stem Cell

Isthmus progenitor cells contribute to homeostatic cellular turnover

The Intestinal Stem Cell Niche Generation and Utilization of

Expression of Stem Cell Markers in HighLET Space RadiationInduced

A constant pool of Lgr5 intestinal stem cells is required for

Inflammationinduced epigenetic imprinting regulates intestinal stem

Regulation of the Intestinal Stem Cell Pool and Proliferation in Drosophila

Identification of Quiescent LGR5 Stem Cells in the Human Colon

Inflammationinduced epigenetic imprinting regulates intestinal stem

Pattern recovery at the base of the crypt is accomplished by cells

LGR5 cells restricted to the lower regions of tumor glands are

Identification of Quiescent LGR5 Stem Cells in the Human Colon

Ubc9 crypts harbor more Lgr5 CBC cells a Confocal images of small

Identification of Quiescent LGR5 Stem Cells in the Human Colon

Isthmus progenitor cells contribute to homeostatic cellular turnover

Nutritional Control of Intestinal Stem Cells in Homeostasis and

Effect of predominant Lactobacillus treatment on ISCs activity A The

Inhibiting NHE1 activity reduced Lgr5 ISCs a UMAP plot highlighting

Reserve Stem Cells in Intestinal Homeostasis and Injury Gastroenterology

The Intestinal Stem Cell Signature Identifies Colorectal Cancer Stem

Lgr5expressing secretory cells form a Wnt inhibitory niche in

Inflammationinduced epigenetic imprinting regulates intestinal stem

Identification of Quiescent LGR5 Stem Cells in the Human Colon

LGR5 from stem cell marker to therapeutic target Trends in Cancer

Impact of aging on function of intestinal stem cells a average mRNA

Enterococcus-derived tyramine hijacks α2A-adrenergic receptor in ...

Enterococcusderived tyramine hijacks 2Aadrenergic receptor in

Establishing chemically induced Paneth cell PCenriched cultures a

ANKRD22 Drives Rapid Proliferation of Lgr5 Cells and Acts as a

Wholemount photograph of small intestine top series and colon

3 Isolation and characterization of Lgr5eGFP ISCs A Schematic

Inflammatory memory restrains intestinal stem cell regeneration PMC

Lgr5expressing secretory cells form a Wnt inhibitory niche in

Young topology enhances regenerative capacity of old ISCs A

Cellular hierarchies and phenotypic plasticity in the intestinal

Inflammatory memory restrains intestinal stem cell regeneration PMC

Frontiers Intestinal Stem Cells and Immune Cell Relationships

The Intestinal Stem Cell Signature Identifies Colorectal Cancer Stem

Znhit1 deletion disrupts postnatal generation of Lgr5 ISC aZnhit1 in

Intestinal stem cells and epithelialmesenchymal interactions in the

Identifying the Stem Cell of the Intestinal Crypt Strategies and

Interleukin IL22 counteracts the selfrenewal of intestinal stem

Stiffness Restricts the Stemness of the Intestinal Stem Cells and Skews

LGR5 Intestinal Stem Cells Display Sex Dependent Radiosensitivityv1

Expansion of Lgr5positive intestinal stem cells is not altered by

Fate mapping in mouse demonstrates early secretory differentiation

Plasticity of Intestinal Epithelium Stem Cell Niches and Regulatory

Heparinbinding epidermal growth factorlike growth factor restores Wnt

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