Human Crl4

Human CRL4 DDB2 ubiquitin ligase preferentially regulates postrepair

PDF Pathogenic Role of the CRL4 Ubiquitin Ligase in Human Disease

IL17RB CRL4 Protein Human Recombinant ProSpec

Human CRL4 DDB2 ubiquitin ligase preferentially regulates postrepair

Frontiers Pathogenic Role of the CRL4 Ubiquitin Ligase in Human Disease

Fig S7 Domain organization of CRL4 subunits The schematic represents

Cullin4 RING ubiquitin ligase complex CRL4 The CRL4 complex has a

The architecture and activation of CRL4 The CRL4 architecture adapted

Detecting UVlesions in the genome The modular CRL4 ubiquitin ligase

CRL4 ligase complex models with different DDB1 conformations A

The role and mechanism of CRL4 E3 ubiquitin ligase in cancer and its

CRL4 complex assembly in the presence and absence of immunomodulatory

Human cytomegalovirus protein RL1 degrades the antiviral factor SLFN11

Architecture of CRL1 SCF and CRL4 ubiquitin ligases SCF ubiquitin

CRBN interacts with DDB1 Cul4A or Cul4B and RoC1 to form the CRL4

E27 replaces endogenous CRL4 substrate receptors A Comparison of the

Human and rabbit SALL4 zinc fingers are direct thalidomidedependent

Modular architecture of CRL4 DCAF complexes Tentative model of the

Full article MEKK1Dependent Activation of the CRL4 Complex Is

3311KH443 inhibitors of E3 CRL4 with anticancer potential Newly

Human CCR4 full length protein-VLP-全长CCR4 膜蛋白-缔码生物

Human CCR4 full length proteinVLPCCR4

The CSN interacts with different CRL4 complexes involved in DDR At the

Characterization of human FCRL4positive B cells

Detecting UVlesions in the genome The modular CRL4 ubiquitin ligase

CRL4 depletion does not impair HIV1 infectivity or viability of

Differential regulation of LSH stability by the counteracting CRL4

Characterization of human FCRL4positive B cells PMC

Cullin4 RING ubiquitin ligase complex CRL4 The CRL4 complex has a

Comparison between the E3ligasesubstrate complexes of the CRL4

Schma comparatif des interactions entre les enzymes CRL1 Skp2 CRL4

Frontiers Arabidopsis CRL4 Complexes Surveying Chromatin States and

CRL4 is activated by NEDD8 in response to TOP1DPCs and target

RCSB PDB 11TL Structure of human CCR4 in complex with GSK2239633A

CRL4 CDT2 interacts with CHK1 in the nucleoplasm A Spatial

Schematic model RepID structural DCAF brings CRL4 on chromatin during

PHIP is the major chromatinassociated CRL4 substrate receptor A

CRL4 Complex Regulates Mammalian Oocyte Survival and Reprogramming by

Expression of the Chemokine Receptors CCR4 CCR5 and CXCR3 by Human

Human CCR4 mice Gene Humanized Mouse Models Biocytogen

CRL4 DCAF8L1 ubiquitinates BARD1 and BRCA1 in vivo and in vitro A

Expression of the Chemokine Receptors CCR4 CCR5 and CXCR3 by Human

CRL4 Cdt2 substrates are degraded in a stereotypical order during early

Human CCR4luc EL4 Cell Lines Biocytogen

CRL4 CRBN E3ubiquitin ligase complex regulation and features of the

CRBN interacts with DDB1 Cul4A or Cul4B and RoC1 to form the CRL4

CRL4 Complex Regulates Mammalian Oocyte Survival and Reprogramming by

Breaking New Ground in Ovarian Cancer Treatment CRL4 Inhibition Shows

Figure 1 from The CRL4 Cdt2 ubiquitin ligase targets the degradation of

CRL4 DDB2 components DDB2 DDB1 and CUL4A are required for restoring

CRL4 is overexpressed in ovarian cancer tissue and cisplatinresistant

PHIP is the major chromatinassociated CRL4 substrate receptor A

CRBN R419X can assemble into a CRL4 E3 ligase complex A schematic

CRL4Cdt2 Coupling Genome Stability to Ubiquitination Trends in Cell

Full article CRL4Cdt2

The Molecular Basis of CRL4DDB2CSA Ubiquitin Ligase Architecture

CryptochromesMediated Inhibition of the CRL4Cop1Complex Assembly

1 Structural models of a CRL CRL4 SV5V PDB id 2HYE Angers et al

PIKES Analysis Reveals Response to Degraders and Key Regulatory

CRL4Cdt2 Coupling Genome Stability to Ubiquitination Trends in Cell

Molecular glues for proteinprotein interactions Progressing toward a

The LongLost Ligase CRL4AMBRA1 Regulates the Stability of DType

Glucoseinduced CRL4COP1p53 axis amplifies glycometabolism to drive

CRL4DCAF1 Ubiquitin Ligase Dependent Functions of HIV Viral Protein R

Full article CRL4Cdt2

Structural modeling of CRL4DDB1CRBN with Cockayne syndrome group A

Cancers Free FullText CRL4CRBN E3 Ligase Complex as a Therapeutic

Glucoseinduced CRL4COP1p53 axis amplifies glycometabolism to drive

CRL4DCAF1 ubiquitin ligase regulates PLK4 protein levels to prevent

The consequences of perturbation of CUL4 CRBN E3 ligase function A

Glucoseinduced CRL4COP1p53 axis amplifies glycometabolism to drive

CRL4Cdt2Mediated Destruction of the Histone Methyltransferase Set8

CRL4CRBN E3 Ligase Complex as a Therapeutic Target in Multiple Myeloma

CCR4 as a Therapeutic Target for Cancer Immunotherapy

CUL4Based Ubiquitin Ligases in Chromatin Regulation An Evolutionary

CRL4Cdt2 Master coordinator of cell cycle progression and genome

CRL4like Clr4 complex in Schizosaccharomyces pombe depends on an

CRL4Cdt2 Coupling Genome Stability to Ubiquitination Trends in Cell

The CRL4DCAF1 cullinRING ubiquitin ligase is activated following a

PIKES Analysis Reveals Response to Degraders and Key Regulatory

CullinRING E3 ubiquitin ligase 4 regulates neurite morphogenesis

USP15 antagonizes CRL4CRBNmediated ubiquitylation of glutamine

CRL4like Clr4 complex in Schizosaccharomyces pombe depends on an

The emerging role for Cullin 4 family of E3 ligases in tumorigenesis PMC

CRL4

CRL4 CRBN

PIKES Analysis Reveals Response to Degraders and Key Regulatory

CRL4like Clr4 complex in Schizosaccharomyces pombe depends on an

The emerging role for Cullin 4 family of E3 ligases in tumorigenesis PMC

p12 possesses an operational PIPdegron at its N terminus A alignment

CRL4DCAF1 Ubiquitin Ligase Dependent Functions of HIV Viral Protein R

The CRL4DCAF1 cullinRING ubiquitin ligase is activated following a

An interactomebased framework for DDB1 and CUL4associated factor

CRL4Cdt2 Ubiquitin Ligase A Genome Caretaker Controlled by Cdt2

The Molecular Basis of CRL4DDB2CSA Ubiquitin Ligase Architecture

CRL4CRBN Targeted Protein Degradation Complex Antibody Sampler Kit

IP 6 promotes CSNCRL4 complex reassembly by augmenting competition

The consequences of perturbation of CUL4 CRBN E3 ligase function A

Direct binding of Cdt2 to PCNA is important for targeting the CRL4Cdt2

Knockdown of crbn or cul4 Impairs Head Development A Schematic

CSNCRL4 CDT2 contains both CUL4A and CUL4B in Sphase A Cell cycle

Glucoseinduced CRL4COP1p53 axis amplifies glycometabolism to drive

CRL4CRBN Targeted Protein Degradation Complex Antibody Sampler Kit

Modeling the CRL4A ligase complex to predict target protein

Frontiers Elucidating the immunomodulatory roles and mechanisms of

The helicase FBH1 is tightly regulated by PCNA via CRL4Cdt2mediated

PIKES Analysis Reveals Response to Degraders and Key Regulatory

PDF The helicase FBH1 is tightly regulated by PCNA via CRL4Cdt2

CRL4DCAF1 ubiquitin ligase regulates PLK4 protein levels to prevent

PIKES Analysis Reveals Response to Degraders and Key Regulatory

The CRL4DCAF1 cullinRING ubiquitin ligase is activated following a

CRL4Cereblon complex in Thalidomide Embryopathy a translational

CRL4CRBN Targeted Protein Degradation Complex Antibody Sampler Kit

BRWD2PHIP associates with CRL4 chromatin regulators and active

CRL4CRBN Targeted Protein Degradation Complex Antibody Sampler Kit

The CRL4DCAF1 cullinRING ubiquitin ligase is activated following a

A summary of CRL4dependent substrates Download Table

Protein kinase ATR inhibits E3 ubiquitin ligase CRL4PRL1 to stabilize

Ovarian Cancer Diagram

Thalidomide Side Effects

PCNA Cell Cycle

Targeted Protein Degradation

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