Fancj Domain

FANCJ helicase domain associates with the MutL complex independent of

Sequence alignment of the FeS domain Human DNA helicases FANCJ and

The helicase domain of FANCJ is required for continuous replication

Frontiers Molecular and cellular functions of the FANCJ DNA helicase

Proposed role of FANCJ in resolving G4 quaduplex DNA during replication

A Domain structure of WRN and FANCJ The right panels depict the

Map of FANCJ protein Download Scientific Diagram

Alignment of helicase motif Ia and model of human FANCJ structure

FANCJ resolves Gquadruplex DNA to maintain genomic stability and

Gquadruplex recognition and remodeling by the FANCJ helicase

FANCJ DNA helicase is recruited to the replisome by AND1 to ensure

FancJ Brip1 lossoffunction allele results in spermatogonial cell

Domain architecture and structure of FANCD2 and FANCI A Schematic of

FANCJ DNA helicase is recruited to the replisome by AND1 to ensure

Analysis of FANCJ AD and FAN1 EH putative homologs in C

Figure 4 from Mutational analysis of FANCJ helicase Semantic Scholar

Proposed model for FANCJ stabilization of FANCD2 and FANCI FANCJ

Model for the cooperation of FANCJ with REV1 and with the WRN and BLM

The FANCJ helicase unfolds DNAprotein crosslinks to promote their

A Domain structure of WRN and FANCJ The right panels depict the

Frontiers Molecular and cellular functions of the FANCJ DNA helicase

Gquadruplex recognition and remodeling by the FANCJ helicase PMC

FANCJ Contributes to Unrestrained Replication and S1 Nuclease

Model for DNA synthesis through G4forming regions A FANCJ possesses

DNA substrate specificity of FANCJ helicase See text for details

FeS cluster in the helicase domain of XPDFANCJ family of DNA

Analysis of FANCJ AD and FAN1 EH putative homologs in C

Domain architecture and structure of FANCD2 and FANCI A Schematic of

A Domain structure of WRN and FANCJ The right panels depict the

FeS cluster in the helicase domain of XPDFANCJ family of DNA

Determination of the Tower domain of FANCD2 a Schematic of FANCI and

FeS cluster in the helicase domain of XPDFANCJ family of DNA

Analysis of FANCJ AD and FAN1 EH putative homologs in C

Domain of a Function on GMAT Concepts Examples

Model depicting the divergent roles of FANCJ in DNA repair and the

The DNA Repair Helicases XPD and FancJ Have Essential IronSulfur

FANCJ regulates FANCD2 focus formation A FAJ mutant and corrected

FANCJ DNA helicase is recruited to the replisome by AND1 to ensure

FANCJ efficiently unwinds unimolecular G4 DNA FANCJ was tested for

Interplay between FANCJ and RPA on G4resolution a Illustration of the

FANCJ is acetylated at lysine 1249 A The Cterminus of FANCJ is

FANCJ unwinds a DNA triple helix in a structurespecific manner The

FeS cluster in the helicase domain of XPDFANCJ family of DNA

Impaired DNA damage induced foci formation in Q mutations of FANCJ and

Frontiers Molecular and cellular functions of the FANCJ DNA helicase

DNA substrate specificity of FANCJ helicase See text for details

FANCJ regulates FANCD2 and BRCA1 chromatin loading A FAJ mutant and

Figure 1 from Mutational analysis of FANCJ helicase Semantic Scholar

A model of how FANCJ proteins function when cells are treated with 5FU

DNA binding activity of FANCJ as detected by gel mobility shift assays

Analysis of FANCJ AD and FAN1 EH putative homologs in C

FANCJ acetylation is induced after DNA damage A Endogenous FANCJ is

A Domain structure of WRN and FANCJ The right panels depict the

Spontaneous DNA damage senescence and replication stress in Fancj

HP1 regulates the localization of FANCJ at sites of DNA doublestrand

Protein schematic of FANCJ orthologs C elegans DOG1 983 aa chicken

Proposed models for how FANCJ protein interactions provide a

Downregulation or loss of FANCJ concomitantly diminishes FANCD2 and

FANCJ regulates FANCD2 stability but FANCD2 has little to no effect on

The FeS cluster in FANCJ is indispensable for helicase activity A

FANCJ regulates FANCD2 and BRCA1 chromatin loading A FAJ mutant and

Knockdown of FANCD2 results in aberrant FANCJ and BRCA1 localization A

DNA damageinducible colocalization of FANCJ helicase and RPA A HeLa

The FANCJ helicase unfolds DNAprotein crosslinks to promote their

FANCJ protein is more stable than FANCD2 and does not significantly

Opposing Roles of FANCJ and HLTF Protect Forks and Restrain Replication

The FeS cluster in FANCJ is indispensable for helicase activity A

FeS cluster in the helicase domain of XPDFANCJ family of DNA

FANCJ can resolve G4 structures ahead of Pol in vitro A Scheme of

The FANCJ helicase unfolds DNAprotein crosslinks to promote their

HLTF Contributes to Fork Degradation in FANCJKO Cells and FANCJ

FANCJ Is a Structurespecific DNA Helicase Associated with the

FANCJ depletion induces qualitative dysregulation in the SCR events

FANCJ unwinds DNA downstream of the Gquadruplex A Representative

The FANCJ helicase unfolds DNAprotein crosslinks to promote their

The Fanconi Anemia Proteins FANCD2 and FANCJ Interact and Regulate Each

DNA damage response of wildtype and mutants FANCJ proteins in cells

Alignment of the FANCJ helicase sequence in Plasmodium spp PfFANCJ is

FANCJ regulates FANCD2 concentration at the protein level A Total

FANCJ and BLM foci formation after cellular exposure to the replication

FANCJ interacts with HP1c in response to DNA damage a Solubilized

FANCJ knockdown leads to loss of ectopic CTGCAG microsatellite signals

Opposing Roles of FANCJ and HLTF Protect Forks and Restrain Replication

MLH1 binding to FANCJ is essential to correct FAJ cells A Myc IP

FANCJ Helicase Uniquely Senses Oxidative Base Damage in Either Strand

A Domain structure of WRN and FANCJ The right panels depict the

The downregulation of FANCJ after transfection of cells with a small

FANCJ Is a Structurespecific DNA Helicase Associated with the

The MSH2MSH6 complex inhibits FANCJ G4 helicase activity A and C

FANCJ regulates FANCD2 and BRCA1 chromatin loading A FAJ mutant and

Understanding The Distinction Between And In Domain And Range QMVSXE

FANCJ helicase controls the balance between short and longtract gene

The FANCJ helicase unfolds DNAprotein crosslinks to promote their

FANCJ Is a Structurespecific DNA Helicase Associated with the

FANCMFAAP24 and FANCJ FA proteins that metabolize DNA PMC

FAlinked FANCJR707C and FANCJH396D mutations and their biochemical

DiseaseCausing Missense Mutations in Human DNA Helicase Disorders PMC

Schematic representation of the architecture of potential helicaseG4

An emerging picture of FANCJs role in G4 resolution to facilitate DNA

Schematic representation of the eleven human Fanconi Anemia proteins

Model of FANCD2 and FANCJ FANCD2 binds FANCJ After monoubiquitination

FAlinked FANCJR707C and FANCJH396D mutations and their biochemical

An emerging picture of FANCJs role in G4 resolution to facilitate DNA

A DNA helicase remodeling proteins How DNAprotein crosslink repair

Fanconi anemia and Blooms syndrome crosstalk through FANCJBLM

Mechanism of FANCJmediated G4unfolding and refolding A Regions of

The Q Motif of Fanconi Anemia Group J Protein FANCJ DNA Helicase

Full article Helicaseinactivating mutations as a basis for dominant

The Q Motif of Fanconi Anemia Group J Protein FANCJ DNA Helicase

Hereditary breast cancer and the BRCA1associated FANCJBACH1BRIP1

Helicases FANCJ RTEL1 and BLM Act on Guanine Quadruplex DNA in Vivo

Expression of FANCJR251C or FANCJQ255H fails to rescue sensitivity of

Purification and determination of iron content in FANCJWT and

FANCJRPA interaction is intact in FA mutant cells Download

PDF Exploring the Gquadruplex binding and unwinding activity of the

Purification and Biochemical Characterization of the G4 Resolvase and

FAJ cells accumulate deletions in regions containing G4 DNA A mutant

FAN1FANCC and FAN1FANCJ double knockout DT40 cells are more sensitive

FANCJRPA interaction is intact in FA mutant cells Download

Client recruitment mechanism of the cytosolic FeS cluster assembly

Fancj Protein Structure

Fanconi Anemia

Fancj Helicase Unstructured Sequence

Fancc Domains

PBC Fancj Protein Structure

Fe S Cluster DNA Helicase Fancj

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