Fancj

Proposed role of FANCJ in resolving G4 quaduplex DNA during replication

Proposed model for FANCJ stabilization of FANCD2 and FANCI FANCJ

Model for DNA synthesis through G4forming regions A FANCJ possesses

Frontiers Molecular and cellular functions of the FANCJ DNA helicase

FANCJ uses its motor ATPase to displace proteins bound to DNA A

The FANCJ helicase unfolds DNAprotein crosslinks to promote their

8Oxoguanine Disrupts GQuadruplex DNA Stability and Modulates FANCJ

The FANCJ helicase unfolds DNAprotein crosslinks to promote their

HP1 regulates the localization of FANCJ at sites of DNA doublestrand

Alignment of helicase motif Ia and model of human FANCJ structure

FANCJ unwinds DNA downstream of the Gquadruplex A Representative

The FeS cluster in FANCJ is indispensable for helicase activity A

FANCJ protein is more stable than FANCD2 and does not significantly

Model depicting the divergent roles of FANCJ in DNA repair and the

FANCJ Contributes to Unrestrained Replication and S1 Nuclease

Impaired DNA damage induced foci formation in Q mutations of FANCJ and

Analysis of FANCJ AD and FAN1 EH putative homologs in C

FANCJ regulates FANCD2 focus formation A FAJ mutant and corrected

DNA binding activity of FANCJ as detected by gel mobility shift assays

FANCJ efficiently unwinds unimolecular G4 DNA FANCJ was tested for

FANCJ Is a Structurespecific DNA Helicase Associated with the

FANCJ unwinds a DNA triple helix in a structurespecific manner The

FANCJ DNA helicase is recruited to the replisome by AND1 to ensure

FANCJ preferentially dissociates from the forked duplex with thymine

FANCJ Is a Structurespecific DNA Helicase Associated with the

Proposed models for how FANCJ protein interactions provide a

Analysis of FANCJ AD and FAN1 EH putative homologs in C

K141K142A mutations in FANCJ abolished Gquadruplex binding but not

FANCJ DNA helicase is recruited to the replisome by AND1 to ensure

FANCJ helicase domain associates with the MutL complex independent of

Opposing Roles of FANCJ and HLTF Protect Forks and Restrain Replication

Map of FANCJ protein Download Scientific Diagram

FANCJ DNA helicase is recruited to the replisome by AND1 to ensure

FANCJ displaces streptavidin from a 5singlestranded DNA tailed

FANCJ and BLM helicases together more efficiently unwind a damaged DNA

FANCJ dysfunction skews gene conversion in favour of LTGC A

FANCJ Gquadruplex DNA unwinding is abolished by the H396D mutation but

FANCJ promotes DNA synthesis through Gquadruplex structures The EMBO

The FANCJ helicase unfolds DNAprotein crosslinks to promote their

Opposing Roles of FANCJ and HLTF Protect Forks and Restrain Replication

FANCJ Is a Structurespecific DNA Helicase Associated with the

FANCJ at the FORK PMC

DNA damage response of wildtype and mutants FANCJ proteins in cells

Frontiers Molecular and cellular functions of the FANCJ DNA helicase

FANCJ DNA helicase is recruited to the replisome by AND1 to ensure

FANCJ Helicase Uniquely Senses Oxidative Base Damage in Either Strand

Effects of FANCJ and MRE11 depletion on chromosomal instability and DNA

Opposing Roles of FANCJ and HLTF Protect Forks and Restrain Replication

Downregulation or loss of FANCJ concomitantly diminishes FANCD2 and

The downregulation of FANCJ after transfection of cells with a small

FANCJ interacts with HP1c in response to DNA damage a Solubilized

The DNA helicase FANCJ BRIP1 functions in double strand break repair

MLH1 binding to FANCJ is essential to correct FAJ cells A Myc IP

FANCJ Is a Structurespecific DNA Helicase Associated with the

FANCJ knockout cells display enhanced sensitivity to the Download

FANCJ is associated with the MRN complex A Coimmunoprecipitation

FANCJ suppresses hypersensitivity to replication inhibitors and

FANCJ patient cells treated with aphidicolin are prone to

FLIM analysis of FancJ in mutant FancJ abolished MEF and knockdown

FANCJ unwinds human telomeric G4 DNA A and B The indicated FANCJ

Helicase assays of FANCJ wildtype and mutants on forked duplex and

The FANCJ helicase unfolds DNAprotein crosslinks to promote their

FANCJ DNA helicase is recruited to the replisome by AND1 to ensure

FANCJ Is a Structurespecific DNA Helicase Associated with the

DNA substrate specificity of FANCJ helicase See text for details

The Fanconi anemia proteins FANCD2 and FANCJ interact and regulate each

The FANCJ helicase unfolds DNAprotein crosslinks to promote their

FANCJ acetylation is induced after DNA damage A Endogenous FANCJ is

FANCJ efficiently unwinds unimolecular G4 DNA FANCJ was tested for

FANCJ efficiently unwinds G4 DNA in an ATP hydrolysisdependent manner

Figure 1 from Mutational analysis of FANCJ helicase Semantic Scholar

An Arabidopsis FANCJ helicase homologue is required for DNA crosslink

Strandspecific inhibition of FANCJ and ChlR1 helicases by the

FANCJ enhances DNA damage-induced polη foci. (a) U2OS cells were ...

FANCJ enhances DNA damageinduced pol foci a U2OS cells were

Figure 1 from Mutational analysis of FANCJ helicase Semantic Scholar

PPT Investigating FANCJ Interaction with DNA Complex Comparative

FANCJ promotes DNA synthesis through Gquadruplex structures The EMBO

FANCJ can resolve G4 structures ahead of Pol in vitro A Scheme of

DNA binding of mutant and wildtype FANCJ proteins as detected by gel

Opposing Roles of FANCJ and HLTF Protect Forks and Restrain Replication

HP1 regulates the localization of FANCJ at sites of DNA doublestrand

Frontiers Molecular and cellular functions of the FANCJ DNA helicase

Opposing Roles of FANCJ and HLTF Protect Forks and Restrain Replication

FANCJ Localization by Mismatch Repair Is Vital to Maintain Genomic

DNA substrate specificity of FANCJ helicase See text for details

A minimal threshold of FANCJ helicase activity is required for its

FANCJ compensates for RAP80 deficiency and suppresses genomic

Figure 1 from Molecular and cellular functions of the FANCJ DNA

FANCJ and BLM helicases together more efficiently unwind a damaged DNA

Interplay between FANCJ and RPA on G4resolution a Illustration of the

M299I FANCJ mutation associated with breast cancer increases the

FANCJ Is a Structurespecific DNA Helicase Associated with the

FANCJ Localization by Mismatch Repair Is Vital to Maintain Genomic

DNA binding of mutant and wildtype FANCJ proteins as detected by gel

DiseaseCausing Missense Mutations in Human DNA Helicase Disorders PMC

FANCMFAAP24 and FANCJ FA proteins that metabolize DNA PMC

A DNA helicase remodeling proteins How DNAprotein crosslink repair

FAlinked FANCJR707C and FANCJH396D mutations and their biochemical

Mechanism of FANCJmediated G4unfolding and refolding A Regions of

An emerging picture of FANCJs role in G4 resolution to facilitate DNA

FAJ cells accumulate deletions in regions containing G4 DNA A mutant

Fanconi anemia and Blooms syndrome crosstalk through FANCJBLM

The Q Motif of Fanconi Anemia Group J Protein FANCJ DNA Helicase

An emerging picture of FANCJs role in G4 resolution to facilitate DNA

Schematic representation of the architecture of potential helicaseG4

The Q Motif of Fanconi Anemia Group J Protein FANCJ DNA Helicase

FAlinked FANCJR707C and FANCJH396D mutations and their biochemical

Purification and Biochemical Characterization of the G4 Resolvase and

Helicases FANCJ RTEL1 and BLM Act on Guanine Quadruplex DNA in Vivo

The Q Motif of Fanconi Anemia Group J Protein FANCJ DNA Helicase

Gquadruplex nucleic acids and human disease Wu 2010 The FEBS

Expression of FANCJR251C or FANCJQ255H fails to rescue sensitivity of

Fanconi anemia and Blooms syndrome crosstalk through FANCJBLM

Figure 1 from The Q Motif of Fanconi Anemia Group J Protein FANCJ DNA

Evaluation of BRIP1 FANCJ and FANCI Protein Expression in Ovarian

The Q Motif of Fanconi Anemia Group J Protein FANCJ DNA Helicase

Schematic representation of FA proteins during ICL repair FANCM

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