Fancd2 Rad51

FANCD2 Colocalizes with RAD51 at Sites of Persistent DSBs AC

FANCD2 functions independently of Rad51 and BRCA2 in response to DNA

FANCD2 and RAD51 nuclear focus formation to assess proximal and distal

Effect of Rad18 or FANCD2 depletion on Rad18 FANCD2 BRCA2 and Rad51

FANCD2 functions independently of Rad51 and BRCA2 in response to DNA

FANCD2 functions independently of BRCA2 and Rad51 in cell survival

Loss of ATM impairs FANCD2 and RAD51 expression and induces DNA damage

Validation of FANCD2 AB RAD51 CD BRCA1 EF BRCA2 GH and

Levels of SCE and Rad51 foci formation in fancd2 cells A

MMCinduced chromatin loading of FancD2 and Rad51 protein Wild type

Inhibition of class I HDACs downregulates RAD51 and FANCD2 on RNA and

MMCinduced chromatin loading of FancD2 and Rad51 protein Wild type

Reduced FANCD2 influences spontaneous SCE and RAD51 foci formation in

FANCD2 and RAD51 nuclear focus formation to assess proximal and distal

Levels of SCE and Rad51 foci formation in fancd2 cells A

MMCinduced chromatin loading of FancD2 and Rad51 protein Wild type

Inhibition of class I HDACs downregulates RAD51 and FANCD2 on RNA and

PDF Reduced FANCD2 influences spontaneous SCE and RAD51 foci

Reduced FANCD2 influences spontaneous SCE and RAD51 foci formation in

FANCD2 and FANCI interact with RAD51 A Pulldown assay with the HeLa

FANCD2 stimulates strand exchange activity by enhancing ssDNA binding

FANCD2 is a central node between repair and cell cycle response to DNA

FANCD2 stimulates strand exchange activity by enhancing ssDNA binding

Noncanonical Roles of RAD51

FBXL12 degrades FANCD2 to regulate replication recovery and promote

Rad18 FANCD2 BRCA2 and Rad51 coimmunoprecipitates and colocalizes

FANCD2 colocalizes with components of the ATM pathway in discrete

DNA repair protein FANCD2 has both ubiquitinationdependent and

RADX Modulates RAD51 Activity to Control Replication Fork Protection

Phosphorylation of FANCD2 Inhibits the FANCD2FANCI Complex and

FANCD2 and FANCI interact with RAD51 A Pulldown assay with the HeLa

Stable RAD51 targeting to the stalled replication forks requires

Figure S3 FANCD2 sisterfoci are not associated with Download

Doublestranded DNA binding function of RAD51 in DNA protection and its

Endogenous RAD51 foci and SCE levels are decreased in FANCD2deficient

Cells Free FullText Noncanonical Roles of RAD51

FANCD2 Maintains Fork Stability in BRCA12Deficient Tumors and

Phosphorylation by ATR triggers FANCD2 chromatin loading and activates

DNA damageinduced Rad51 nuclear focus formation is not impaired in the

PDF FANCIFANCD2 stabilizes the RAD51DNA complex by binding RAD51

A) FANCD2 (green) co-localizes with γ-H2AX, MRE11 and RPA (red) at ...

A FANCD2 green colocalizes with H2AX MRE11 and RPA red at

FANCD2 and FANCI exhibit different monoubiquitination responses A

FANCD2 protects genome stability by recruiting RNA processing enzymes

PTEN is required for efficient mitomycin Cinducible FANCD2 and FANCI

Regulation of RAD51 at the Transcriptional and Functional Levels What

FANCD2 pre v ents DNA2 and MRE11 mediated nascent DNA degradation A

FA family proteins FANCD2 and FANCI are significantly reduced in MTDH

FANCD2 Antibody BSA Free NB100182 by Novus Part of BioTechne

FanconiAnemiaAssociated Mutations Destabilize RAD51 Filaments and

Doublestranded DNA binding function of RAD51 in DNA protection and its

Models for the FANCD2 function in the FA pathway A Locations of the

Doublestranded DNA binding function of RAD51 in DNA protection and its

Replication stress induces accumulation of FANCD2 at central region of

Fanconi anemiaassociated mutation in RAD51 compromises the coordinated

Domain architecture and structure of FANCD2 and FANCI A Schematic of

FANCD2 Protects Cells from Replication Stress and Preserves Genomic

Early Role of RAD51 in Promoting Replication Fork Restart A

A novel role for nonubiquitinated FANCD2 in response to hydroxyurea

Germcell and meiotic pairing abnormalities in Fancd2 mice A B

Fanconi anemia protein FANCD2 is activated by AICAR a modulator of

FANCD2 protects genome stability by recruiting RNA processing enzymes

Phosphorylation by ATR triggers FANCD2 chromatin loading and activates

RADX controls RAD51 filament dynamics to regulate replication fork

HEL308 colocalizes with sites of DNA replication as well as RAD51 and

Figure 3 Clinical Significance of FANCD2 Gene Expression and its

FANCD2 depletion alters DNA replication process and leads to genomic

Ringshaped FANCD2 foci colocalize with known APB components and

Noncanonical Roles of RAD51

Phosphorylation by ATR triggers FANCD2 chromatin loading and activates

FanconiAnemiaAssociated Mutations Destabilize RAD51 Filaments and

DNA requirement in FANCD2 deubiquitination by USP1UAF1RAD51AP1 in the

CyclinDependent KinaseMediated Phosphorylation of FANCD2 Promotes

RAD51 paralog function in replicative DNA damage and tolerance PMC

FANCD2 foci assemble in a Rloop dependent manner A Download

Figure 2 from The Fanconi Anemia Proteins FANCD2 and FANCJ Interact and

FANCD2 Alchetron The Free Social Encyclopedia

CyclinDependent KinaseMediated Phosphorylation of FANCD2 Promotes

FANCD2 protects genome stability by recruiting RNA processing enzymes

FANCD2 facilitates replication through common fragile sites PMC

DNA robustly stimulates FANCD2 monoubiquitylation in the complex with

FANCD2 protects against bone marrow injury from ferroptosis PMC

Codepletion of POLQ and FANCD2 or BRCA2 markedly increase sensitivity

Subcellular localization of FANCD2 is associated with survival in

Role of UAF1 and RAD51AP1 DNA binding in FANCD2 deubiquitination a

Summary of the data in a hypothetical model showing the functional

Elucidation of the Fanconi Anemia Protein Network in Meiosis and Its

A Distinct Replication Fork Protection Pathway Connects Fanconi Anemia

Frontiers Enhanced sensitivity robust p21 activation and sustained

A Distinct Replication Fork Protection Pathway Connects Fanconi Anemia

PDF Structural insight into FANCIFANCD2 monoubiquitination

Rad18 is required for functional interactions between FANCD2 BRCA2

Dynamic FA pathway model The FANCD2FANCI dimer represents the

Two variants of FANCD2 namely FANCD2V1 V1 for the longknown

Rad18 is required for functional interactions between FANCD2 BRCA2

A Distinct Replication Fork Protection Pathway Connects Fanconi Anemia

Rad18 is required for functional interactions between FANCD2 BRCA2

Oncology Letters

Rad18 is required for functional interactions between FANCD2 BRCA2

The Fanconi anemia repair pathway The FA core complex consisting of

FANCJ Uses Its Motor ATPase to Destabilize ProteinDNA Complexes

Figure 1 from Fanconi Anemia Complementation Group D2 FANCD2

The FEBS Journal Vol 286 No 1

FIGNL1 inhibits homologous recombination in BRCA2 deficient cells by

Inhibition of HDAC123 and knockdown of HDAC2 downregulate RAD51 A

The expanding roles of homologous recombination proteins in genome

Frontiers Integrative analyses of prognosis tumor immunity and

PP2A licenses the FANCD2FANCI complex for chromosome loading Cell Reports

Preventing Nonhomologous End Joining Suppresses DNA Repair Defects of

GFPFancd2 localization in tissues a Representative GFPFancd2

PDF Moonlighting at replication forks a new life for homologous

Rad18 is required for functional interactions between FANCD2 BRCA2

ATRFANCIFANCD2

A FAD2 cells stably expressing LacZ FANCD2WT FANCD2K561R

A Distinct Replication Fork Protection Pathway Connects Fanconi Anemia

The Fanconi anemia pathway induces chromothripsis and ecDNAdriven

结构速递 | 一周“结构”要览 VOL.68(6.19~6.25)|BCDX2|蛋白质|DNA|线粒体|结构|-健康界

VOL68619625BCDX2DNA

The FANCIFANCD2 complex links DNA damage response to Rloop regulation

Hypomorphic Mutations in the Gene Encoding a Key Fanconi Anemia Protein

Fanci FANCD2 RAD51

RAD18 FANCD2 RAD51 Pathway

BRCA1 RAD51 Centromere

RAD51 Recombinase

RAD18 Macrophgy

RAD51 shRNA Cell Drived Xenograft

FANCD2 and ssDNA

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