Elp3 Complex

The Elongator subunit Elp3 is a noncanonical tRNA acetyltransferase

Structures of the Elp1 Elp2 and Elp3 subunits and the Elp456

The Elongator subunit Elp3 is a noncanonical tRNA acetyltransferase

Mutations at the SAM domain but not at the HAT domain of elp3 perturb

Model of the individual steps of the Elp3 modification reaction

Elp3 tRNAcm 5 U34 methyl transferase is an ancient enzyme The Elp3

The Elongator complex and its components a Schematic view of the Elp

ELP3 stabilizes cMyc to promote tumorigenesis PMC

PCNA is associated with the Elp3 complex AB PCNA copurified with

Full article Elongator a conserved complex required for wobble

The Elongator subunit Elp3 is a noncanonical tRNA acetyltransferase

Structures of the Elp1 Elp2 and Elp3 subunits and the Elp456

The conserved residues in the rSAM and KAT domains of Elp3 are required

Model of the proteome structure of the Elongator complex Download

Frontiers Loss of Elp3 Impairs the Acetylation and Distribution of

Failure of AtELP3 to complement the elp3 D mutant despite interaction

ELP3 Controls Active Zone Morphology by Acetylating the ELKS Family

An IronSulfur Cluster Domain in Elp3 Important for the Structural

ELP3 Controls Active Zone Morphology by Acetylating the ELKS Family

Elp3 and Elp4 promote cell migration and invasion of HepG2 cells The

Purification of Elongator complex Cell lysates from 293T cells stably

Architecture of the yeast Elongator complex PMC

Hemocytes in Elp3 mutants Hemocytes from control and Elp3 larvae were

An IronSulfur Cluster Domain in Elp3 Important for the Structural

The histone acetyltransferase Elp3 plays in active role in the control

Elp3 suppresses cell growth in 293T cells A The effect of FlagElp3

The Elongator complex and its components a Schematic view of the Elp

Purification and Characterization of the Human Elongator Complex

RCSB PDB 5L7L Crystal Structure of Elp3 from Dehalococcoides

Disruption of each subunit of the Elongator complex leads to similar

Amyloid pathology reduces ELP3 expression and tRNA modifications

Phylogenetic and sequence analysis of Elp3 orthologues A ELP3a and

An IronSulfur Cluster Domain in Elp3 Important for the Structural

Elp3 colocalizes with 1433 and is required for proper chromatin

ELP3 Controls Active Zone Morphology by Acetylating the ELKS Family

Elp3 interacts with and stabilizes Snail1 through inhibiting its

ELP3 Controls Active Zone Morphology by Acetylating the ELKS Family

Elp3 is required for cranial neural crest CNC migration in explants

ELP3 Controls Active Zone Morphology by Acetylating the ELKS Family

ELP3 expression in normal endometrium and endometrioid adenocarcinoma

Elp3 deficiency in intestinal epithelial cells of Apcmin mice impairs

ELP3 Controls Active Zone Morphology by Acetylating the ELKS Family

The Elongator Subunit Elp3 Regulates Development Stress Tolerance

Elp3 is important for hyphal growth and conidiation in A fumigatus

ELP3 is essential for RB1CC1mediated ferroptosisassociated

Figure 1 from Role of Elongator Subunit Elp3 in Drosophila melanogaster

A second catalytic domain in the Elp3 histone acetyltransferases a

The enzymatic activity of Elp3 is not required for the effects of

Hemocytespecific expression of Elp3 RNAi reduces hemocyte number and

Expression of the Elp3 during early Xenopus development a RTPCR

Restoration of Elp3 stability and Elongator subunit interactions in an

Elp3 deficiency in Lgr5 cells impairs Wntdriven tumor initiation A

Cells expressing elp3 sitespecific mutants with mutations at the HAT

ELP3 Recombinant Rabbit mAbKD

The Elongator subunit Elp3 is a noncanonical tRNA acetyltransferase

Morpholinoinduced knockdown of ELP3 affects motor neuron axonal

ELP3 stabilizes cMyc to promote tumorigenesis PMC

A novel ELP1 mutation impairs the function of the Elongator complex and

Domain architecture and phylogeny of the Elp3 and GcnE proteins A A

Elp3 promotes Tuft cell differentiation A LoxP sites flanking exon 2

ELP3 Recombinant Rabbit mAbKD

Western blot analysis of ELP3 protein expression in human control

Domain architecture and phylogeny of the Elp3 and GcnE proteins A A

Proposed structural rearrangements of Elp3 during tRNA modification a

Elp3 deficiency in intestinal epithelial cells of Apcmin mice impairs

Loss of Elp3 upregulates global protein synthesis in hematopoietic

Elp3 promotes radiationinduced intestinal regeneration A left

ELP3 Controls Active Zone Morphology by Acetylating the ELKS Family

Elp3 interacts with and stabilizes Snail1 through inhibiting its

Elp3 deficiency in intestinal epithelial cells of Apc min mice

Purification and Characterization of the Human Elongator Complex

Elp3 is required for tumor development in a mouse model of colon

Elp3 promotes Tuft cell differentiation A LoxP sites flanking exon 2

Elp3 is important to resist DNA damaging agents in the absence of Asf1

Elp3 modulates neural crest and colorectal cancer migration requiring

Loss of Elp3 alters the expression of genes involved in carbohydrate

SAM domain not HAT domain mediates ELP3 protective effect in the

Expression of ELP3 gene in HeLa cells A Northern blot products of

Reaction and regulatory mechanisms of Elongator A Overview of

Fig Role of the Elongator complex A DNA methylation or demethylation

IJMS Free FullText Elongator Subunit 3 Elp3 Is Required for

Molecular Architecture StructureFunction Relationship and Importance

Elongator Subunit 3 Elp3 Is Required for Zebrafish Trunk Development

Elongator Protein 3 Elp3 Lysine Acetyltransferase Is a Tailanchored

Reconstitution of Elongator subunit interactions by AtELP3

Molecular Architecture StructureFunction Relationship and Importance

Human Elongator facilitates RNA polymerase II transcription through

DERP6 ELP5 and C3ORF75 ELP6 Regulate Tumorigenicity and Migration

Molecular Architecture StructureFunction Relationship and Importance

Elp6L126Q destabilizes Elp456 a Structural overview of the Elongator

Elongator Controls the Migration and Differentiation of Cortical

Crystal structure of DmcElp3 a Overall structure of DmcElp3 shown in

A Novel Histone Acetyltransferase Is an Integral Subunit of Elongating

Fig Role of the Elongator complex A DNA methylation or demethylation

Overexpression of mtELP3 results in an increase in the expression of

Elongator Subunit 3 Elp3 Is Required for Zebrafish Trunk Development

CryoEM structure of yeast Elp123 showing its active site A Atomic

a Domain structure of Elp3related proteins from various organisms

A Dynamic Unfolded Protein Response Contributes to the Control of

Elongator Protein 3 Elp3 Lysine Acetyltransferase Is a Tailanchored

ELP3203 isoform is a mitochondrial matrix protein A Subcellular

Structural insights into the function of Elongator PMC

Elongator Protein 3 Elp3 Lysine Acetyltransferase Is a Tailanchored

Overexpression of mtELP3 results in an increase in mitochondrial

The predicted backbone structures of the three eLP domains of the human

Elongator Protein 3 Elp3 Lysine Acetyltransferase Is a Tailanchored

Elp3deficicent progenitors do not show signs of activation of the UPR

Elongator Controls the Migration and Differentiation of Cortical

Direct observation of structure and dynamics during phase separation of

Elp1p and Elp3p coimmunoprecipitate tRNA Glu UUC A T7transcribed

Elp3deficient PyMT tumors lack a Lef1dependent gene signature A

BloodBased Biomarkers Reflecting Protease 3 and MMP12 Catalyzed

Diphthamide player Dph3 also partakes in tRNA modification A Dph3

Functional divergence of the two Elongator subcomplexes during

Elp1p and Elp3p coimmunoprecipitate tRNA Glu UUC A T7transcribed

A SPAACmediated and Sfpmediated conjugation of the ELP scaffolds

Direct observation of structure and dynamics during phase separation of

Engineered ElastinLike Polypeptides Intelligent SelfAssembling

Role of ELK3 in Ferroptosis of Rheumatoid Arthritis Fibroblastlike

ELP3 Enzymatic Reaction

Immunofluorescence ELP3

Elongator Complex RNAPII

ELP1 Western Blot

ELP2 Western Blot

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