D2 Msn

MERFISH identifies molecularly distinct D1 and D2 MSN subtypes in

Opposite modulation of D1 and D2 MSN activity in aDLS during

Functional brainwide responses dynamically change upon D1 and D2 MSN

Photoinhibition of CINs Differentially Decreases D1 and D2 MSN

HFSInduced LTD at Corticostriatal Afferents to D2 MSN and D1 MSN A

D1 and D2 medium spiny neurons in the nucleus accumbens core have

Frontiers The transcription factor Zfp503 promotes the D1 MSN

D1 and D2 medium spiny neurons in the nucleus accumbens core have

Frontiers The transcription factor Zfp503 promotes the D1 MSN

Indirect Pathway Projection Intensities in D2 MSNSpecific Fto Knockout

D1 and D2 medium spiny neurons in the nucleus accumbens core have

Dopamine modulates MSN cell excitability A Representative

D1 and D2 medium spiny neurons in the nucleus accumbens core have

Frontiers The transcription factor Zfp503 promotes the D1 MSN

The molecular and spatial features of MSN subtypes underlie anatomic

Frontiers The transcription factor Zfp503 promotes the D1 MSN

The maturation of D1 MSNs occurs earlier than that of D2 MSNs A

Transcriptional features of MSN subtypes correlate with their spatial

Optogenetically evoked D1D2 MSN activity in the vl CPu A Histological

D2 Receptors Bidirectionally Control the Extent of Bridging Collaterals

Rhes travels from D2R MSN to D1R MSN in vitro A confocal livecell

Visualization of MSN and nNOSIN for LCM A H Staining of 8 m m

Balanced D1D2 MSN activity during continuous walking but not movement

Validation of MSN subtype specific transcriptomics with D1 or D2MSN

Balance of D1 and D2 MSNs firing rates as a function of cortical input

Dopamine D2 receptors bidirectionally regulate striatal enkephalin

HighFrequency Activation of Nucleus Accumbens D1MSNs Drives

Overlapping Striatal Circuits and Molecular Mechanisms in Rodent Models

Working model Switch between the D1RMSN and D2RMSN activation states

2017-10-19 | 投射腹侧苍白球区的D1和D2-MSN在可卡因成瘾中的不同作用

20171019 D1D2MSN

A thalamic input to the nucleus accumbens mediates opiate dependence PMC

Mitochondrial length in NAc shell D1MSN and D2MSN dendrites a

Direct and Indirect Pathway MSNs Respond Differently to Bilateral

Distinct role of nucleus accumbens D2MSN projections to ventral

D1and D2MSN Projection to the VP A Schematic of experiment B

DREADDmediated silencing of D2MSN terminals in the VP enhances

Transient depression of D2MSN lateral inhibition induced by

Selective suppression of NMDA current in D2MSN lacking RGS9 2 A

d2 d2 OKFNM

Distinct role of nucleus accumbens D2MSN projections to ventral

Expression of MCT8 and OATP1C1 in D2MSN indirect pathway mediumsized

D2R upregulation reduces D2MSN inhibitory transmission to ventral

HighFrequency Activation of Nucleus Accumbens D1MSNs Drives

Mitochondrial length in NAc shell D1MSN and D2MSN dendrites a

D1MSN efferents are distinct and separable from D2MSN efferents

Représentation schématique de la transmission mésolim-bique ...

Reprsentation schmatique de la transmission msolimbique

A037 Decoding neuronal vulnerability integrative analysis of D1r and

Summary of major differences between D1RMSNs and D2RMSNs based on

Complementary cognitive roles for D2MSNs and D1MSNs during interval

HighFrequency Activation of Nucleus Accumbens D1MSNs Drives

Distinct role of nucleus accumbens D2MSN projections to ventral

Schematic illustration of the microcircuit of the striatum dMSN

Different Roles of D1D2 Medium Spiny Neurons in the Nucleus Accumbens

D2MSNs are required for cue recall a Time plot and b heat map

Distinct role of nucleus accumbens D2MSN projections to ventral

Expression of MCT8 and OATP1C1 in D1MSN direct pathway mediumsized

Verification of single cell RTPCR method A Example of single cell

DREADDmediated silencing of D2MSN terminals in the VP enhances

DA depresses D2MSN lateral inhibition and produces a small

NLG1

D1R and D2Rexpressing MSNs are randomly distributed in the rostral

NeuronD1D2

Transient depression of D2MSN lateral inhibition induced by

Dynorphin suppresses GABA neurotransmission from D1MSN and D2MSN

Mitochondrial length in NAc shell D1MSN and D2MSN dendrites a

Proposed encoding of VLS MSNs Schematic illustration of basal ganglia

Enhancer AAV toolbox for accessing and perturbing striatal cell types

Mitochondrial length in NAc shell D1MSN and D2MSN dendrites a

D2R upregulation reduces D2MSN inhibitory transmission to ventral

Astrocytes increased their adjacency to D1MSN synapses but retracted

Proposed encoding of VLS MSNs Schematic illustration of basal ganglia

Advanced Science

The molecular and spatial features of neuron subtypes underlie

Brief and prolonged D1 and D2MSN stimulation differentially modulate

NeuronD1D2

Transient depression of D2MSN lateral inhibition induced by

Creinducible AAV miRNA knockdown of Egr3 in D1MSN and D2MSN

D2MSNs are required for cue recall a Time plot and b heat map

Transient depression of D2MSN lateral inhibition induced by

Etomidate selectively activates tonic receptors in D2 MSNs A

NAc Core D2MSN neurotransmitter release blockade reduces the latency

Engineering of D1or D2MSNspecific YCnano50 or ArchTEGFP mice A

Nucleus Accumbens Microcircuit Underlying D2MSNDriven Increase in

Transient depression of D2MSN lateral inhibition induced by

Activation of indirectpathway D2MSNs inhibits cocaine Download

D2MSN

Complementary cognitive roles for D2MSNs and D1MSNs during interval

D2MSN M2 shows an earlier response to the NoGo stimulus than D1MSN

Overlapping Striatal Circuits and Molecular Mechanisms in Rodent Models

Nucleus Accumbens Microcircuit Underlying D2MSNDriven Increase in

Evidence for dosedependent effects of activation of frontostriatal

Nucleus Accumbens Microcircuit Underlying D2MSNDriven Increase in

Complementary cognitive roles for D2MSNs and D1MSNs during interval

Optogenetic stimulation of ChIs decreases sEPSCs frequency in D2MSNs

Complementary cognitive roles for D2MSNs and D1MSNs during interval

Selective modulation of D2MSNs via excitatory G q or inhibitory G

Nucleus Accumbens Microcircuit Underlying D2MSNDriven Increase in

PDF Distinct role of nucleus accumbens D2MSN projections to ventral

Differences between MSNMSN and FSIMSN synapse properties Download Table

Dorsal Striatal D1and D2MSN Population Activity Displayed Similar

5HT1BRs mediate part of the DA depression of D2MSN lateral inhibition

Nucleus Accumbens Microcircuit Underlying D2MSNDriven Increase in

D2R upregulation in D2MSNs does not alter D1MSN activity in vivo a

Nucleus Accumbens Microcircuit Underlying D2MSNDriven Increase in

MSN D1 vs D2

D2 MSN Marker

D1 MSN D2 MSN Amygdala

MSN D1 D2 Mediated Siganling

MSN D1 D2 Receptor PDE10A

MSN D1 D2 Signaling PDE10A

D1 and D2 MSN Projections From NAC

D1 vs D2 MSN Projections Model Loop

D1 D2 MSN Triosome in Striatal

MSN D2 Striatum Optogenetics Depression

GPR-6 D2 MSN Indirect Pathway

MSN Knocking

MSN D2 Striatum Optogenetics Dantidepressant

MSN's Neurons

2Msn

D1 vs D2 MSN Excitability Whole Cell Electrophysiology Accumbens

MSN's Striatum Synapse

Sucrose D1 D2 MSN

NAC MSN D1 D2 Circuit

D1 D2 MSN Reward and Aversion

D1 MSN D2 MSN Huntington's

MSN Particle

D1 MSN D2 MSN Antibody

Dopamine On D1 and D2 MSN Neuron

D2 MSN Location in Brain

Dynorphin and D1 and D2 MSN

D1 D2 MSN LTP

Striatal D1 and D2 MSN Control Circuit

D1 D2 MSN LTP LTD

D1 and D2 MSN Control Circuit

D1 and D2 MSN Circuit

D1 and D2 MSN Neurons

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