Cryptic Exon

Cryptic exon located upstream of TDP43binding sites on Nfasc mRNA is

TDP43 represses cryptic exon inclusion in the FTDALS gene UNC13A

Cryptic exon incorporation occurs in Alzheimers brain lacking TDP43

TDP43 regulates cryptic exon splicing in hMNs ab Visualization of

Nuclear depletion of TDP43 causes cryptic exon inclusion in UNC13A RNA

TDP43 represses cryptic exon inclusion in FTDALS gene UNC13A bioRxiv

TDP43 and other hnRNPs regulate cryptic exon inclusion of a key ALS

TDP43 maximizes nerve conduction velocity by repressing a cryptic exon

TDP43 represses cryptic exon inclusion in the FTDALS gene UNC13A PMC

Identification of a cryptic exon in Nup188 as a TDP43 target A

TDP43 and other hnRNPs regulate cryptic exon inclusion of a key ALS

Identification of a cryptic exon in NUP188 as a TDP43 target A

TDP43 represses cryptic exon inclusion in FTDALS gene UNC13A bioRxiv

TDP43 and other hnRNPs regulate cryptic exon inclusion of a key ALS

TDP43 represses cryptic exon inclusion in the FTDALS gene UNC13A

TDP43 and other hnRNPs regulate cryptic exon inclusion of a key ALS

Cryptic exon inclusion in TDP43 proteinopathies opportunities and

PDF Differential exon usage and cryptic exon profiles of TDP43 loss

Figure 1 from Differential exon usage and cryptic exon profiles of TDP

TDP43 represses cryptic exon inclusion in the FTDALS gene UNC13A

TDP43 and other hnRNPs regulate cryptic exon inclusion of a key ALS

Differential expression of cryptic exon genes ASignificantly

TDP43 and other hnRNPs regulate cryptic exon inclusion of a key ALS

PDF TDP43 and other hnRNPs regulate cryptic exon inclusion of a key

Differential expression of cryptic exon genes a Significantly

TDP43 represses cryptic exon inclusion in the FTDALS gene UNC13A

Fig S1 A AARS1 cryptic exon inclusion percentage for various cell

UNC13A cryptic exon inclusion is detected in disease relevant tissues

Splice donor site mutations lead to cryptic splice site use or exon

PDF Cryptic exon incorporation occurs in Alzheimers brain lacking

Cryptic exon incorporation occurs in Alzheimers brain lacking TDP43

Identification of a cryptic exon in Nup188 as a TDP43 target A

Cryptic exon incorporation in TBPHdeficient flies Visualization of

PDF TDP43 represses cryptic exon inclusion in the FTDALS gene UNC13A

HnRNP involvement in cryptic exon repression Several hnRNP proteins

Fig S1 A AARS1 cryptic exon inclusion percentage for various cell

Struggling with TDP43 mislocalization Try cryptic exon splicing

Cryptic exon incorporation occurs in Alzheimers brain lacking TDP43

Activation of cryptic splice site at c48CT in MECP2 exon 1 A

Differential expression of cryptic exon genes ASignificantly

ab Cloning of cryptic exon 1c a RTPCR products are shown Total RNA

PDF Correction TDP43 and other hnRNPs regulate cryptic exon

Correction of the cryptic exon inclusion by antisense oligonucleotides

ab Identification of cryptic exon 18a a RTnested PCR amplification

PDF Cryptic intron activation within the large exon of the mouse

Detection of cryptic exon incorporation in AD brain tissue DNA

Splicing analysis using MAJIQ demonstrates inclusion of cryptic exon

PDF Cryptic intron activation within the large exon of the mouse

Kuz cryptic exon is retained in S2R cells Sashimi plots were used to

Novel cryptic exon event in gene At1g02840 splicing factor SR1 In the

PDF TDP43 represses cryptic exon inclusion in FTDALS gene UNC13A

SpeciesDependent Splice Recognition of a Cryptic Exon Resulting from a

UNC13A cryptic exon inclusion is detected in disease relevant tissues

Germline mutations in the new E1 cryptic exon of the VHL gene in

LLPSdeficient TDP43 supports exon skipping in endogenous genes

Inclusion of cryptic exons by alternative splicing The observed

Cryptic inclusions UNCover losses driving neurodegeneration Trends in

Tdp43 cryptic exons are highly variable between cell types a While

Cryptic exons and inclusion outcomes BioRender Science Templates

Identification of TDP43associated cryptic exons Homo sapiens A

Identification of Tdp43associated cryptic exons Mus musculus A

Tdp43 cryptic exons are highly variable between cell types Abstract

The accumulation of UNC13A cryptic RNA is sensitive to TDP43 levels

Tdp43 cryptic exons are highly variable between cell types Abstract

The accumulation of UNC13A cryptic RNA is sensitive to TDP43 levels

Mechanism of STMN2 cryptic splicepolyadenylation and its correction

Identification of Tdp43associated cryptic exons Mus musculus A

TDP43 repression of nonconserved cryptic exons is compromised in ALS

The extreme Nterminus of TDP43 is required to repress UNC13A cryptic

Mechanism of STMN2 cryptic splicepolyadenylation and its correction

Cryptic splicing of stathmin2 and UNC13A mRNAs is a pathological

Cryptic exons and microexons Download Scientific Diagram

PDF Tdp43 cryptic exons are highly variable between cell types

Cryptic exons created by two deep intron mutations causing

Differential exon usage events shared by TDP43 knockdown and

Validation of human cryptic exons and their detection in ALSFTD brain

Normal and aberrant splicing of exon 4 a and exon 9 b due to

Human and mouse hnRNP L cryptic exons viewed in the UCSC Genome Browser

Evidence of TDP43 binding cryptic exons a Results of MEME motif

Detection of cryptic exons in the amygdala from Alzheimers disease

Detection of STMN2 and KALRN cryptic exons in singlenuclei sequencing

Novel antibody shows specificity for HDGFL2 with cryptic peptide A

Full article Cryptic splicing common pathological mechanisms involved

Neuronspecific cryptic exons CaMKIICreTardbp FF knockout mice

Detection of STMN2 and KALRN cryptic exons in singlenuclei sequencing

Transcripts containing cryptic exons are rapidly degraded qRTPCR for

Mechanisms of CRISPRinduced exon skipping a From Li et al 6

Scoring cryptic splice sites against canonical splice sites

Analysis of the cryptic exons X and Y in human retina and fibroblast

EJCdepletion leads to activation of cryptic 5 splice sites A

Detection of STMN2 and KALRN cryptic exons in singlenuclei sequencing

Cryptic exons use a RSlike splicing mechanism A Schematic of

Scoring cryptic splice sites against canonical splice sites

Cryptic exons created by two deep intron mutations causing

Tdp43 cryptic exons are highly variable between cell types Abstract

Neuronspecific cryptic exons CaMKIICreTardbp FF knockout mice

Schematic diagram of cryptic splicing patterns Most genes are split

Cryptic exons and microexons Download Scientific Diagram

Neuronspecific cryptic exons CaMKIICreTardbp FF knockout mice

Exon Recognition in Vertebrate Splicing Journal of Biological

Frontiers TDP43 and NEAT long noncoding RNA Roles in

A fluid biomarker reveals loss of TDP43 splicing repression in

Validation of additional splicing targets af Depletion of TDP43

Stressinduced TDP43 nuclear condensation causes splicing loss of

TDP43 regulates STMN2 RNA and protein levels through direct

Abnormal Splicing Events due to Loss of Nuclear Function of TDP43

Depletion of TDP43 exacerbates tauopathydependent brain atrophy by

Misspliced transcripts generate de novo proteins in TDP43related ALS

Figures and data in TDP43 maximizes nerve conduction velocity by

Depletion of TDP43 from iPSC derived motor neurons iPSCMNs and iPSC

Figures and data in TDP43 maximizes nerve conduction velocity by

ALS IMPLICATED PROTEIN TDP43 SUSTAINS LEVELS OF STMN2 A MEDIATOR OF

Figures and data in TDP43 maximizes nerve conduction velocity by

Neuroscience Cryptic exons reveal some of their secrets eLife

Blocking CA repeats mimics depletion of hnRNP L in inclusion of the

Research The Wong Laboratory

Exonintron organisation of the AR gene and frequent pathogenic AR mRNA

Consensus Guidelines for the Design and In Vitro Preclinical Efficacy

Ligandindependent androgen receptor variants derived from splicing of

Cryptic Exon Inclusion

Stmn2 Cryptic Exon

Cryptic Exon Splicing

Unc13a Cryptic Exon

Cryptic Exon Arv7

Oncogene Cryptic Exon

Station Cryptic Exon Primers

Ferroptosis Cryptic Exon

Exon Mutation

Gene Exon and Intron

Mutation Cryptic Exon Structure

Cryptic Exon Switch Schematic

Unc13a WT and Cryptic Exon

TDP-43 Cryptic Exon Splicing

Unc13a Cryptic Exon Sequence

Cryptic Exon Inclusion Cartoion

Poldip3 Cryptic Exon

Splicing Dysfunction Cryptic Exon

A Diagram Showing Unc13a with Cryptic Exon Inclusion

Atg4b Cryptic Exon Gemonic Locus

Structure of Cryptic Exon 2A in Stathmin2

Hdgfl2 Cryptic Exon

Androgen Receptor

Minigene Assay

What Is a Cryptic Exon TDP-43

Canonical Splice Site

ESR1 Cryptic Exon

Mirna Splicing

Poison Exon

Diaphragmatic Hernia Adult

Aalternative Splicing

USH2A Exon

Schwann Cells

Somatic and Germline Mutations

AR Protein Structure Exon 1

Stmn2 Exon Antibody to Detect Cryptic Splicing

Era of Cryptic Exons

BRCA2 Exons

Intron Mutation Effect

Cryptic Coloration in Animsla

Kryptic Mutation

What Is a Cyptic Human

What Is a Constitutive Exon

Exon 11 BRCA2

Exon Inclusio

Unc13a Cryptic Peptide

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