Crkl

The CRKL Adaptor Protein Transforms Fibroblasts and Functions in

Crk and CrkL as Therapeutic Targets for Cancer Treatment

CRKL JCGA

CRKL promotes hepatocarcinoma through enhancing glucose metabolism of

CRKL Wikipedia

GLI2 binds directly to the 2nd intron of CRKL gene A Schematic view

Fulllength structures of CRK and CRKL predicted by MD simulation A

CRKL overexpression promotes cancer cell growth a A549 cells were

CRKL Recombinant Rabbit mAbKD

CRKL secretion and cell signaling A CRKL is secreted by DU145 cells

CRKL Enhances YAP Signaling through Binding and JNKJUN Pathway

Subcellular targeting of CRKL to focal adhesions rescues motility

CRK and CRKL interact with C3G and CASL to regulate T cell diapedesis

CRKL secretion and cell signaling A CRKL is secreted by DU145 cells

CrkL versus CrkII in integrin signaling i Integrin activation

CRKL secretion and cell signaling A CRKL is secreted by DU145 cells

CrkL versus CrkII in integrin signaling i Integrin activation

CRKL inhibits apoptosis of Ishikawa cells A CRKL transfection

Diagram of cancers that are dependent on Crk and CrkL for tumor cell

CRKL mediates ALK signaling and regulates cytoskeleton cell migration

CRKL transfection promotes cell proliferation and cell cycle in the

CRKL is a target gene of GLI2 A 3day MTT proliferation results of

CRKL is a miR200 target that regulates integrindependent signaling

Crk and Crkl Are Required in the Endocardial Lineage for Heart Valve

Crk and CrkL as Therapeutic Targets for Cancer Treatment

Interplay of the Protooncogene Proteins CrkL and CrkII in Insulinlike

Glucose metabolism is a common target of Crk and Crkl deficiency A

Figure 3 from The CRKL Adaptor Protein Transforms Fibroblasts and

Crk and CrkL as Therapeutic Targets for Cancer Treatment

CrkL regulates granule secretion and MTOC polarization Human NK cells

AB Schematic summary of CRK and CRKL adapter proteins for FGFR their

Interplay of the Protooncogene Proteins CrkL and CrkII in Insulinlike

Fulllength structures of CRK and CRKL predicted by MD simulation A

Inhibitory RNAs directed against Crk and CrkL effectively reduce

Adapter molecules Crk and CrkL are novel desmosome constituents A

Subcellular localization of CrkL in migrating cells A to C

The CRKL Adaptor Protein Transforms Fibroblasts and Functions in

Interplay of the Protooncogene Proteins CrkL and CrkII in Insulinlike

Downregulation of CrkL expression by siRNA in CrkIIIdeficient MEFs

CrkL associates with nephrin and forms a heterooligomer with Crk2 a

Crk and Crkl are required for allocating NCCs to form the dorsal ASP

Increased Soluble CrkL in Serum of Breast Cancer Patients Is Associated

Fulllength structures of CRK and CRKL predicted by MD simulation A

Dosagedependent requirement of Crk and Crkl in NCCs for cardiac OFT

Crkl is an essential gene A Restriction map of the insert of

CRKL enhanced the in vitro migration and invasion capacities of 786O

The CRKL Adaptor Protein Transforms Fibroblasts and Functions in

CrkL is upregulated in myelogenous leukemia cells A Expression of

CRKL transfection promotes cell proliferation and cell cycle in the

Essential roles of Crk and CrkL in fibroblast structure and motility

Crk and Crkl are required for allocating NCCs to form the dorsal ASP

CrkL promotes cervical cancer cell invasion through Src signaling

CrkL knockdown reduces Dox resistance and increases apoptosis in

Interplay of the Protooncogene Proteins CrkL and CrkII in Insulinlike

CRKL inhibits apoptosis of Ishikawa cells A CRKL transfection

CRKL is sufficient to promote LAUD cell viability and invasion A Cell

CrkL and CrkII participate in the generation of the growth inhibitory

WAVE2 is required for phosphorylation of CrkL and C3G A Jurkat T

CrkL functions as a nuclear adaptor and transcriptional activator in

CrkL inhibits RANKLRANK reverse signaling pathway ab Primary

CRKL Mediates p110β-Dependent PI3K Signaling in PTEN-Deficient Cancer ...

CRKL Mediates p110Dependent PI3K Signaling in PTENDeficient Cancer

CRKL cDNA expression profile a cDNA expression profile of two

CRKL Enhances YAP Signaling through Binding and JNKJUN Pathway

Subcellular localization of CrkL in fibroblasts that express active

CRKL upregulation in cervical cancer and its negative correlation with

The Adapter Protein Crkl Links Cbl to C3G after Integrin Ligation and

CrkL is upregulated in myelogenous leukemia cells A Expression of

Bidirectional positive regulation of CRKL and AFAP1AS1 A The level

CrkL is required for NKG2Dmediated conjugate formation but not Akt or

Crk and Crkl Are Required in the Endocardial Lineage for Heart Valve

Interplay of the Protooncogene Proteins CrkL and CrkII in Insulinlike

CrkL is upregulated in myelogenous leukemia cells A Expression of

CRKL Enhances YAP Signaling through Binding and JNKJUN Pathway

Increased Soluble CrkL in Serum of Breast Cancer Patients Is Associated

The Adapter Protein Crkl Links Cbl to C3G after Integrin Ligation and

Figure 5 from Amplification of CRKL induces transformation and

CRKL promotes glucose metabolism of hepatocarcinoma cells by activating

Crkl Is Complexed with Tyrosinephosphorylated Cbl in Phpositive

CrkL and CrkII participate in the generation of the growth inhibitory

A Expression of CRKL protein in LSCC cell lines and nontumor

CRKL knockdown inhibits RMS cell growth shCRKL knockdown CRKL

Binding of CrkL to fulllength C3G A Schematic representation of the

Interaction between CRKL and 1 integrin A The association of CRKL

CRKL Knockdown Suppresses PI3K Signaling and Growth of PTENDeficient

Suppression of CRKL decreases the proliferation of NSCLC cells that

CRKL dictates antiPD1 resistance by mediating tumorassociated

CrkL versus CrkII in integrin signaling i Integrin activation

CrkL Phosphorylation and Association with cAbl during Inhibition by

CrkL functions as a nuclear adaptor and transcriptional activator in

CRKL Recombinant Rabbit mAbKD

CrkL is a coactivator of estrogen receptor alpha that enhances

Essential roles of Crk and CrkL in fibroblast structure and motility

Genomic and functional analysis identifies CRKL as an oncogene

Expression of CrkL protein in cervical carcinoma tissues A Negative

Subcellular localization of CrkL in migrating cells A to C

Amplification and overexpression of CRKL gene in NSCLC cell lines that

CrkL inhibits RANKLRANK reverse signaling pathway ab Primary

Specificity of CRKL knockdown a To determine if the CRKL affect on

TGFdependent CrkL phosphorylation and neural crest differentiation

Proposed Model of the CRKCRKL Signaling Network in Metazoans and

Structural and dynamic properties of CrkL a Structure of CrkL The

Oncology Letters

Proposed Model of the CRKCRKL Signaling Network in Metazoans and

Domains of Crk and its binding partners Schematic diagram of the

【文章解读】IF=25.7 肝细胞癌免疫耐药机制研究：CRKL 的关键作用及联合治疗策略 - 知乎

IF257 CRKL

Phylogeny of CRK CRKL and Their Orthologs The maximum likelihood

再次发文！复旦李辉、郭磊、叶青海、樊嘉合作等发现CRKL调控抗PD-1耐药性的潜在机理-《转》译-转化医学网-转化医学核心门户

CRKLPD1

Reduced smooth muscle differentiation of NCCs in CrkCrkl cko versus

【合作文章，IF=25.7】CyTOF发现CRKL通过介导肝癌中肿瘤相关中性粒细胞浸润调控抗PD-1耐药性 - 知乎

IF257CyTOFCRKLPD1

Models of Crk Adaptor Proteins in Cancer Emily S Bell Morag Park 2012

Lyn is required for the functions of CrkLC3G complex in neutrophils

Analysis of potential CRKLregulated alternative splicing events and

Quantitative assessment of glioblastoma phenotypes in vitro establishes

Experimental Characterization of the Interaction between the NTerminal

Understanding CrRLK1L Function Cell Walls and Growth Control Trends

IF257 CRKL

CrkL兔单克隆抗体(CrkL Rabbit mAb) CrkL兔单抗(WB,ICC/IF)

CrkLCrkL Rabbit mAb CrkLWBICCIF

Oncology Letters

USP53 binds stabilizes and deubiquitinates CRKL ab Knockdown of

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