Cdc6

CDC6 as a Key Inhibitory Regulator of CDK1 Activation Dynamics and the

CDKs Give Cdc6 a License to Drive into S Phase Cell

Schematic model of the regulation of Cdc6 throughout the cell cycle

Model of events linking CDC6 and CDK2 activation during exit from

Analysis of Cdc6 function in the assembly of mammalian prereplication

The subcellular localization of CDC6 is cell cycle regulated A

Summary of the temporal order of regulatory events affecting Cdc6

Cdc6 as a novel target in cancer Oncogenic potential senescence and

CDC6 Gene GeneCards CDC6 Protein CDC6 Antibody

cdc6

Cdc6 contributes to cisplatinresistance by activation of ATRChk1

Cdc6 as a novel target in cancer Oncogenic potential senescence and

Cdc6 is regulated by E2F and is essential for DNA replication in

CDC6 as a Key Inhibitory Regulator of CDK1 Activation Dynamics and the

The Cdc6 WHD undergoes multiple conformational changes from ORCCdc6 to

MyoD occupies the Cdc6 promoter in myoblasts A Schematic of the Cdc6

Necessary Cooperation of CDC6 and CDT1 for Origin Refiring A

Cdc6 is regulated by E2F and is essential for DNA replication in

Model for the role of human CDC6 in replicationcheckpoint activation

Cdc6 is sequentially regulated by PP2ACdc55 Cdc14 and Sic1 for

CDC6 knockdown inhibits lung cancer cell proliferation colony

Cdc6 ATPase Activity Regulates ORCCdc6 Stability and the Selection of

CDC6 regulates downstream signalings related to cell cycle and

Structural change in Orc1 that accommodates Cdc6 binding and activates

Cdc6 ATPase Activity Regulates ORCCdc6 Stability and the Selection of

CDC6 as a Key Inhibitory Regulator of CDK1 Activation Dynamics and the

Cdc6 is regulated by E2F and is essential for DNA replication in

Cdc6 promotes rDNA transcription initiation in an ATPbinding and

Cdc6 ATPase Activity Regulates ORCCdc6 Stability and the Selection of

The Role and Regulation of the preRC Component Cdc6 in the Initiation

Cdc6 protein levels are only detected in differentiated endoreplicating

Cdc6 is regulated by E2F and is essential for DNA replication in

CDC6 Gene GeneCards CDC6 Protein CDC6 Antibody

The DNA replication protein Cdc6 inhibits the microtubuleorganizing

CDC6 Is Induced during PCa Progression and Is Positively Correlated

Cleavage of Cdc6 induces nuclear accumulation of tCdc6 proteins Cells

CDC6 genes from related yeast repress fulllength CDC6 but produce

Cdt1 and Cdc6 Are Destabilized by Rereplicationinduced DNA Damage

The functional role of Cdc6 in SG2M in mammalian cells EMBO reports

CDC6 protein expression in cell cycle mutants A Indicated strains

Cdc6 is regulated by E2F and is essential for DNA replication in

Cdc6 depletion induces chromosome instability A Flow cytometry of

Ectopic expression of Cdc6 promotes DNA replication after meiosis I in

Differential condensation of sister chromatids acts with Cdc6 to ensure

Figures and data in Cdc6 ATPase activity disengages Cdc6 from the pre

Ectopic expression of Cdc6 promotes DNA replication after meiosis I in

Cdc6 contributes to cisplatinresistance by activation of ATRChk1

CDC6 Gene GeneCards CDC6 Protein CDC6 Antibody

CDC6 is expressed at significantly higher levels in the endometrial

Cdc6 addition promotes premature initiation of DNA replication in G 1

Cdc6 Stability Is Regulated by the Huwe1 Ubiquitin Ligase after DNA

Cdc6 interacts in vivo with Cdc2 kinase A Cdc6 coimmunoprecipitates

Cdc6 degradation requires phosphodegron created by GSK3 and Cdk1 for

Multiple short protein binding motifs in ORC1 and CDC6 control the

Blocked Cdc6 ATP hydrolysis leads to formation of an Download

Cytoplasmic Retention of CDC6 Induces Premature Senescence in

Cdc6 inhibits DNA replication after origin licensing at an earlier

Caspase3mediated Cleavage of Cdc6 Induces Nuclear Localization of p49

CDC6 Is Induced during PCa Progression and Is Positively Correlated

Targeted Destruction of DNA Replication Protein Cdc6 by Cell Death

Cdc6 is sequentially regulated by PP2ACdc55 Cdc14 and Sic1 for

Figures and data in Cdc6 is sequentially regulated by PP2ACdc55 Cdc14

Cdc6 ATPase activity disengages Cdc6 from the prereplicative complex

CDC6 and HPV oncoprotein expression Download Scientific Diagram

Cdc6 ATPase activity disengages Cdc6 from the prereplicative complex

CDC6 S phase Strair YCpG2CDC6 to midlog pha added and the hydroxyurea

Cytoplasmic Retention of CDC6 Induces Premature Senescence in

Cdc6 Stability Is Regulated by the Huwe1 Ubiquitin Ligase after DNA

Figures and data in Cdc6 ATPase activity disengages Cdc6 from the pre

Degradation of Cdc6 at the G1S transition occurs via a CRL A Cdc6

Characterization of the CDC6 K3R and S106A mutantsa CDC6 K3R and

The Role and Regulation of the preRC Component Cdc6 in the Initiation

CDC6 expression was further verified in HCC patient specimens and cell

Cdc6 ATPase activity disengages Cdc6 from the prereplicative complex

Cdc6 is sequentially regulated by PP2ACdc55 Cdc14 and Sic1 for

Cdc6 transcriptionally represses Ecadherin a and b Ecadherin

Cdc6 depletion induces chromosome instability A Flow cytometry of

Schematic of Cdc6 protein A Schematic of the N terminal 48 amino

CDC6 interacts with an H1 kinase in vitro and in vivo and is a

The functional role of Cdc6 in SG2M in mammalian cells EMBO reports

The Nterminal domain of Cdc6 interferes with Mcm chromatin loading

Expression and localization of Cdc6 proteins in normal BMMCs and

Cdc6 is important for E7 expressing cells to alleviate G1 arrest under

ORCCdc6 binds nonspecifically to DNA in the absence of Cdc6 ATPase

Cdc6 is regulated by E2F and is essential for DNA replication in

Roles of the CDK Phosphorylation Sites of Yeast Cdc6 in Chromatin

Sitedirected mutagenesis of the CDC6 gene at its nucleotidebinding

Cdc6 associates with Clb2 A Cdc6 forms a complex with Clb2 Cdc28

Roles of the CDK Phosphorylation Sites of Yeast Cdc6 in Chromatin

CDC6 regulates cell cycle progression and apoptosis in B cell lymphoma

Cdc6 is sequentially regulated by PP2ACdc55 Cdc14 and Sic1 for

CDC6 is phosphorylated as cells enter S phase A CV1 cells were

Interaction of human CDC6 and ATR A GSTCDC6 was incubated with HeLa

CDC6 Knockdown Increases the Sensitivity of PCa Cells to Treatment with

The functional role of Cdc6 in SG2M in mammalian cells EMBO reports

Cell cycle and cell growthregulated proteolysis of mammalian CDC6 is

The Role of Cell Cycle Division 6 CDC6 in Cancer Breast Cancer as a

The 3 Rs of Cdc6 Recruitment Regulation and Replication Current Biology

The Coordination between DNA Replication Initiation and Other Cell

The Cdc6p nucleotidebinding motif is required for loading Mcm proteins

Cdc6Induced Conformational Changes in ORC Bound to Origin DNA Revealed

The Role of Cell Cycle Division 6 CDC6 in Cancer Breast Cancer as a

Structure and Function of Cdc6Cdc18 Molecular Cell

The Role of Cell Cycle Division 6 CDC6 in Cancer Breast Cancer as a

Structure and Function of Cdc6Cdc18 Molecular Cell

Downregulation of Cdc6 a Cell Cycle Regulatory Gene in Prostate

Mapping of the DNAbinding domain of Cdc6 A A scheme of fulllength

Distribution of Cdc6YFP during late G2 and M phase A The punctual

The Role of Cell Cycle Division 6 CDC6 in Cancer Breast Cancer as a

PDF Control of cell cycle progression by phosphorylation of cyclin

Regulation of CDC6 Geminin and CDT1 in Human Cells that Undergo

CDKs Promote DNA Replication Origin Licensing in Human Cells by

Chromosomal DNA synthesis in cdc61 and transformants Yeast cdc61

Regulation of CDC6 Geminin and CDT1 in Human Cells that Undergo

Juvenile Hormone Activates the Transcription of Celldivisioncycle 6

CDKs Promote DNA Replication Origin Licensing in Human Cells by

Cdc6 Downstream of CDK2

Cdc6 Plane

Orc DNA

Role of Cdc6 in Cell Cycle

Cdk1 Activation

Cdc6 Level Cell Cycle

Accenture Cdc6 Pallavaram

Cdk1 Inhibitor

Cdc6 Binding to Orc

Pre-Replication Complex

Cdt1 and Cdc6 Recruitment

ATPase Activity of Human Cdc6

Origin Recognition Complex

Replication Science

Mcm2-7

CDH1 and APC

Pre Replicative Complex

DNA Helicase

Eukaryotic Replication Fork

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