Caspr2 Structure

Tertiary structure of CASPR2 adapted from SaintMartin et al 2018

Characterization of Caspr and Caspr2 transgenes A Schematic

Structure and celladhesion function of Caspr2 A Axoglial complexes

Structural Characterization of the Extracellular Domain of CASPR2 and

Characterization of Caspr and Caspr2 transgenes A Schematic

Caspr and Caspr2 Are Required for Both Radial and Longitudinal

The Caspr2 cytoplasmic region promotes enrichment at the AIS A The

RCSB PDB 5Y4M Discoidin domain of human CASPR2

Neuropathic Pain and Distinct CASPR2 Autoantibody IgG Subclasses Drive

Transcriptional regulation network of CNTNAP2 A and the Caspr2

Structure and expression of Caspr constructs A Schematic

Structural Characterization of the Extracellular Domain of CASPR2 and

Structure and expression of Caspr constructs A Schematic

Neuropathic Pain and Distinct CASPR2 Autoantibody IgG Subclasses Drive

Caspr2 autoantibodies target multiple epitopes Neurology

Loss of Caspr1 and Caspr2 Affect Preand Postsynaptic Integrity at the

Structural Characterization of the Extracellular Domain of CASPR2 and

Structure and signaling pathways of CaSR ECD Extracellular domain

Structural Characterization of the Extracellular Domain of CASPR2 and

Loss of Caspr1 and Caspr2 Results in Myelinated Axon Pathology A TEM

Delayed onset of severe chronic pain in CASPR2 autoantibodyassociated

Caspr2 interacts with type 1 inositol 145trisphosphate receptor in

Caspr and Caspr2 Are Required for Both Radial and Longitudinal

Diagram of the CASPR2 constructs and hydrodynamic characterization of

The Caspr2 cytoplasmic region promotes enrichment at the AIS A The

The somatodendritic internalization of Caspr2 requires PKC

Caspr and Caspr2 Are Required for Both Radial and Longitudinal

Caspr2 interacts with type 1 inositol 145trisphosphate receptor in

Association of TAG1 and Caspr2 in brain and transfected COS7 cells

The CASPR2 cell adhesion molecule functions as a tumor suppressor gene

Caspr2 autoantibodies target multiple epitopes Neurology

Structural Characterization of the Extracellular Domain of CASPR2 and

Association of Caspr2 with TAG1 A Association of TAG1 and Caspr2

Cis and trans interactions between TAG1 and Caspr2 in COS7 cells

Localization of Caspr2 in Myelinated Nerves Depends on AxonGlia

Characterization of Caspr and Caspr2 transgenes A Schematic

Localization of Caspr2 in Myelinated Nerves Depends on AxonGlia

Autoantibodies Hurt Transfer of PatientDerived CASPR2 Antibodies

Characterization of Caspr and Caspr2 transgenes A Schematic

Distribution of Caspr2 at presynaptic sites of excitatory and

Diagram depicting the putative in solution structure of the

Male Caspr2 mutant mice exhibit faster colonic bead expulsion while

Lgi1 And Caspr2 Antibodies HNDVWL

Caspr2 interacts with type 1 inositol 145trisphosphate receptor in

Caspr2 autoantibodies target multiple epitopes Neurology

Caspr2 and TAG1 are colocalized within axonal transport vesicles A

Human CASPR2 Antibodies Reversibly Alter Memory and the CASPR2 Protein

Caspr1 and Caspr2 Are Required for the Retention of K V 12 Channels at

IUCr Structure of a CRISPRassociated protein Cas2 from Desulfovibrio

CASPR2 autoantibody characterization Download Scientific Diagram

Caspr1 and Caspr2 Ablation Leads to 41B Mislocalization in Myelinated

Axonal Domain Disorganization in Caspr1 and Caspr2 Mutant Myelinated

CASPR2 Regulates the Excitability of DRG Neurons A Representative

Surface CASPR2 is expressed in inhibitory axons and in inhibitory

Distribution of Caspr2 and K channels in peripheral nerves from

Serum from Caspr2 immunized mice binds Caspr2 A IgG from serum of

Neuromyotonia and CASPR2 Antibodies Electrophysiological Clues to

Characterization of Caspr and Caspr2 transgenes A Schematic

Localization of Caspr2 in Myelinated Nerves Depends on AxonGlia

CASPR2 General Information Sino Biological

Organization of Myelinated Axons by Caspr and Caspr2 Requires the

Juxtaparanodal accumulation of PSD93 depends on Caspr2 and TAG1

The value of LGI1 Caspr2 and voltagegated potassium channel

Immunoglobulin G in the mouse brains and CASPR2 expression A

Neuropathic Pain and Distinct CASPR2 Autoantibody IgG Subclasses Drive

Characterization of Caspr2 transgenes Download Scientific Diagram

SAXS rigid body model of CASPR2 Single rigid body model model 4 of

AntiCASPR2 antibodies clinical significance and its main phenotypes

Model of the molecular components of the juxtaparanode The

Frontiers Inhibitory axons are targeted in hippocampal cell culture

Ion channels PPTX

Caspr2FL and Caspr2dPDZ colocalize and associate with K channels

Single particle EM of the extracellular domain of CASPR2 A raw image

Model of the molecular organization of juxtaparanodal regions This

A schematic model describing the role of Caspr in the processing and

Caspr2 a New Member of the Neurexin Superfamily Is Localized at the

Caspr proteins organize myelinated axons A schematic drawing

Mosaic structures of different members of the Caspr family All Caspr

Caspr2 a New Member of the Neurexin Superfamily Is Localized at the

The binding sites of Caspr2Fc are localized on the somatodendritic

A Domain organization of CaSR protein showing extracellular

Candidate autism gene screen identifies critical role for celladhesion

Caspr2 a New Member of the Neurexin Superfamily Is Localized at the

SASDBR2 Contactinassociated proteinlike 2 Caspr2 extracellular

Neuronal autoantigenspathogenesis associated disorders and antibody

Autoantibodies associated with diseases of the CNS new developments

Humoral signatures of Caspr2antibody spectrum disorder track with

Candidate autism gene screen identifies critical role for celladhesion

Schematic model describing molecular interactions at the juxtaparanodal

Inhibitory axons are targeted in hippocampal cell culture by anti

The expression of the Caspr22 deletion mutant is restricted to the

Candidate autism gene screen identifies critical role for celladhesion

Caspr induces the expression of an LMw isoform of contactin on the cell

Effects of IgG on CASPR2transfected HEK cells A Representative

Proteins binding to Caspr2 The black bar on the lefthand side

A Relative number of CD8Caspr2 contacts in PLPwt n 6 and PLPtg

Effects of IgG on CASPR2transfected HEK cells A Representative

Ultrastructural organization of myelinated fibers and nerve function in

The Caspr2Fc binding sites are localized at postsynaptic contacts

Permissive central tolerance plus defective peripheral checkpoints

Candidate autism gene screen identifies critical role for celladhesion

Caspr2 a New Member of the Neurexin Superfamily Is Localized at the

Candidate autism gene screen identifies critical role for celladhesion

生命学院刘俊杰、陈春来团队合作发现CRISPR免疫增效子建立Cas9核酸酶生长进化模型-清华大学

CRISPR Cas9

Candidate autism gene screen identifies critical role for celladhesion

In vivo Mechanisms of AntibodyMediated Neurological Disorders Animal

A schematic model describing the role of Caspr in the processing and

Permissive central tolerance plus defective peripheral checkpoints

Amplified image of contactinassociated protein 2 Caspr2positive

Endoglycosidase H digestion reveals improper cellular trafficking for

Humoral signatures of Caspr2antibody spectrum disorder track with

CRISPRCas9

Morphology of the nodal environs in Caspr2 mice EM pictures of

Persistent microglial activation and synaptic loss with behavioral

Caspr2 Protein

Caspr2 Protein Structure

Neuromyotonia

Caspr2 and CNTNAP2 Structure

Anti Caspr2 Antibody

CNTNAP2 Gene

Glycophorin C Structure

Early Endosome

Caspr2 Encephalitis

Caspr2 Channlopathy

Crisper CAS2 Structure

Caspr2 Antibody Hippocampal

Caspr2 Encephalitis MRI

Faciobrachial Dystonic Seizures

Caspr2 Antibody Cerebellum

Caspr1 Brain Slice

Caspr2 Myelinated Axon

El Caspr

Juxtaparanode Caspr2

Strep Pyrogenes Structure

Juxtaparnode Caspr2 Encephalitis

Caspr Immunofluorescence

Anti Caspr2 Antibody Encephalitis

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